ReviewKidney international reports2016
Renal Stress Testing in the Assessment of Kidney Disease.
Review in Kidney international reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Furosemide stress test as a predictive marker of acute kidney injury progression or renal replacement therapy: a systemic review and meta-analysis.Critical care (London, England) · 2020Pooled it
- Glomerular filtration rate reserve is reduced during mild passive heat stress in healthy young adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Trial
- Renal functional reserve predicts GFR response to empagliflozin in RENALIS and RACELINES clinical trials.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026Observational
- Assessment, molecular mechanisms and therapeutic targets for renal functional reserve.Renal failure · 2025Review
- Molecularly Targeted Cancer Medications and Kidney Health.JAMA network open · 2025Article
- Role of Spot Urine Sodium in Furosemide Stress Test in Volume-overloaded Critically Ill Patients with Acute Kidney Injury.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Amino acids to prevent cardiac surgery-associated acute kidney injury: a randomized controlled trial.JA clinical reports · 2024Article
- Hemodynamic Renal Reserve Response in Conscious Normotensive and Hypertensive Mice.Kidney & blood pressure research · 2024Article
- Urine Quantification Following Furosemide for Severe Acute Kidney Injury Prediction in Critically Ill Children.Journal of pediatric intensive care · 2023Article
- Acute kidney disease: an overview of the epidemiology, pathophysiology, and management.Kidney research and clinical practice · 2023Article
- Acute kidney injury biomarker olfactomedin 4 predicts furosemide responsiveness.Pediatric nephrology (Berlin, Germany) · 2023Article
- Neutrophil-to-lymphocyte ratio is a marker for acute kidney injury progression and mortality in critically ill populations: a population-based, multi-institutional study.Journal of nephrology · 2022Article
- Quantitative renal magnetic resonance imaging: magnetic resonance urography.Pediatric radiology · 2022Review
- Risk factors for acute kidney injury in neonates with congenital diaphragmatic hernia.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Assessment of nephron number and single-nephron glomerular filtration rate in a clinical setting.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Review
- Role of the Furosemide Stress Test in Renal Injury Prognosis.International journal of molecular sciences · 2020Review
- The furosemide stress test for prediction of worsening acute kidney injury in critically ill patients: A multicenter, prospective, observational study.Journal of critical care · 2019Observational
- Dynamic Biomarker Assessment: A Diagnostic Paradigm to Match the AKI Syndrome.Frontiers in pediatrics · 2019Review
- Cortical Perfusion and Tubular Function as Evaluated by Magnetic Resonance Imaging Correlates with Annual Loss in Renal Function in Moderate Chronic Kidney Disease.American journal of nephrology · 2019Observational
- Haemodynamic or metabolic stimulation tests to reveal the renal functional response: requiem or revival?Clinical kidney journal · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As part of human evolutionary development, many human organ systems have innate mechanisms to adapt to increased "work demand" or stress. This reserve capacity can be informative and is used commonly in cardiology to assess cardiac function (e.g., treadmill test). Similarly, the kidney possesses reserve capacity, which can be demonstrated in at least 2 of the following renal domains: glomerular and tubular. When appropriate stimulants are used, healthy patients with intact kidneys can significantly increase their glomerular filtration rate and their tubular secretion. This approach has been used to develop diagnostics for the assessment of renal function. This article reviews both glomerular and tubular kidney stress tests and their respective diagnostic utility.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.