Evidence map›Paper›PMID 29142799›Full record

ReviewCureus2017

Respiratory Failure Following Organophosphate Poisoning: A Literature Review.

Pirthvi Raj Giyanwani, Ujala Zubair, Osama Salam, Zarafshan Zubair

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  15. Article
  16. Clinical Profile and Outcome of Patients with Acute Poisoning Admitted in Intensive Care Unit of Tertiary Care Center in Eastern Nepal.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2018
    Article
  17. High Dose of Pralidoxime Reverses Paraoxon-Induced Respiratory Toxicity in Mice.Turkish journal of anaesthesiology and reanimation · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pirthvi Raj GiyanwaniCivil Hospital Karachi, Dow University of Health Sciences (DUHS), Karachi, Pakistan.
Ujala ZubairMedicine, Dow University of Health Sciences (DUHS), Karachi, Pakistan.
Osama SalamSindh Medical College, Dow University of Health Sciences (DUHS), Karachi, Pakistan.
Zarafshan ZubairMBBS, Dow University of Health Sciences (DUHS), Karachi, Pakistan.
Dow University of Health Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organophosphates (OPs) account for a large portion of suicides globally. OP manifests as cholinergic crises, which underlie respiratory failure. There are many pathways by which respiration is inhibited secondary to organophosphate poisoning. These include central as well as peripheral mechanisms, with central mechanisms predominating. We conducted a literature review in June 2017. PubMed, Embase, and Google Scholar were searched for studies that reported acute organophosphate poisoning in humans. In our review, data were collected from studies published during the years 2001 to 2016. The data consisted of 1,996 patients with organophosphate poisoning, of which 491 (24.6%) required ventilatory support secondary to respiratory failure. Treatment offered to OP poisoning patients should focus on its pathophysiology to benefit from the future outcomes. Recent advances direct the need for a central nervous system (CNS) protective strategy for future prevention and treatment of events associated with cholinergic crises.

Indexed as

clinical trialsorganophosphate poisoningrespiratory failure

Identifiers

PMID29142799
PMCPMC5669523
OpenAlexW2750630051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.