ArticleChemical science2015
How to split a G-quadruplex for DNA detection: new insight into the formation of DNA split G-quadruplex.
Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Enzyme-Free DNA Logic Circuit with Single-Color Readout for Dual Biomarker Detection.Applied biochemistry and biotechnology · 2026Article
- Comparative Analysis of Crystal Violet-Binding Aptamers as Potential Cores for Binary Sensors.International journal of molecular sciences · 2025Article
- Topological effect of an intramolecular split G-quadruplex on thioflavin T binding and fluorescence light-up.Chemical science · 2024Article
- Activatable G-quadruplex based catalases for signal transduction in biosensing.Nucleic acids research · 2023Article
- Identifying and Differentiating Topological G-Quadruplex Structures with DNA-Encoded Plasmonic Gold Nanoparticles.Angewandte Chemie (International ed. in English) · 2022Article
- Split G-Quadruplexes Enhance Nanopore Signals for Simultaneous Identification of Multiple Nucleic Acids.Nano letters · 2022Article
- Zippered G-quadruplex/hemin DNAzyme: exceptional catalyst for universal bioanalytical applications.Nucleic acids research · 2021Article
- FeChemical science · 2021Article
- Tuning the conformation of G-quadruplexes by sodium and potassium ions: application to photometric and fluorometric determination of amyloid β(1-40).Mikrochimica acta · 2021Article
- Article
- Target-activated transcription for the amplified sensing of protease biomarkers.Chemical science · 2020Article
- Toward a Rational Approach to Design Split G-Quadruplex Probes.ACS chemical biology · 2019Article
- Exploration of intramolecular split G-quadruplex and its analytical applications.Nucleic acids research · 2019Article
- G-Quadruplexes as An Alternative Recognition Element in Disease-Related Target Sensing.Molecules (Basel, Switzerland) · 2019Review
- DNAzyme Catalyzed Tyramide Depositing Reaction forTheranostics · 2019Article
- Alphanumerical Visual Display Made of DNA Logic Gates for Drug Susceptibility Testing of Pathogens.Chembiochem : a European journal of chemical biology · 2018Article
- A universal probe design for colorimetric detection of single-nucleotide variation with visible readout and high specificity.Scientific reports · 2016Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Here, we get a new insight into the formation of a split G-quadruplex from the viewpoints of the split mode and guanine base number. An unusual result is that the split mode 4 : 8 performed best in six split modes, including the frequently used mode 1 : 3 and 2 : 2 in the split G-quadruplex enhanced fluorescence assay. Circular dichroism spectra verified the conclusion. The application of the split G-quadruplex based assay in DNA detection was performed on the point mutations of the JAK2 V617F and HBB genes. A multi-target analysis method based on a pool of G-segments split from T30695 (GGGTGGGTGGGTGGGT) by the magic "law of 4 : 8" was established.
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