Evidence map›Paper›PMID 29142561›Full record

ArticlePakistan journal of medical sciences

Feto-maternal outcomes and Glycemic control in Metformin versus insulin treated Gestational Diabetics.

Rabia Arshad, Samia Khanam, Fuad Shaikh, Nasim Karim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 5 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Rabia ArshadDr. Rabia Arshad, MBBS, M. Phil, Assistant Professor, Department of Pharmacology, Altamash Institute of Dental Medicines, Karachi, Pakistan.
Samia KhanamDr. Samia Khanam, MBBS, M. Phil, Assistant Professor and Head, Department of Pathology, Altamash Institute of Dental Medicines, Karachi, Pakistan.
Fuad ShaikhDr. Fuad Shaikh, MBBS, M.Phil, Associate Professor, Department of Pharmacology, Dow University of Health Sciences, Karachi, Pakistan.
Nasim KarimDr. Nasim Karim, MBBS, M. Phil, Ph D, Post Doc (USA), Head of Pharmacology Department, Bahria University Medical and Dental College, Sailors Street, Adjacent PNS Shifa, Defence Phase-II, Karachi, Pakistan.
Karachi Medical and Dental College · PKBahria University · PKDow University of Health Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate and compare feto-maternal outcomes and glycemic control in metformin versus insulin treated gestational diabetics.

methodsThe study was conducted in 2010- 2012 as a part of M. Phil at Civil hospital, Lyari General Hospital and Mamji Hospital in Karachi. After written informed consent, 71 GDM diagnosed females with WHO criteria were enrolled. They were divided into two groups. Group-A, 32 females were given oral metformin 500 mg TDS while Group-B, 39 females were given insulin 0.8-0.9 mg/kg/day in two divided doses subcutaneously. Patients were followed till term. Feto-maternal outcomes were evaluated in 25 patients in each group who completed the study.

resultsWhen groups were compared, newborns in Group-B were significantly more in weight (p=0.01). Significant numbers of babies were delivered after 38 weeks of pregnancy in Group-B (P=0.021). There were two intrauterine deaths and significantly higher HbA

conclusionMetformin has produced better effects on feto-maternal outcomes and glycemic control in comparison to Insulin in GDM.

Indexed as

Fetal outcomesGestational diabetesInsulinMaternal outcomesMetformin

Identifiers

PMID29142561
PMCPMC5673730
OpenAlexW2766087058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.