ArticlePharmacognosy magazine2017
Growth-arresting Activity of Acmella Essential Oil and its Isolated Component D-Limonene (1, 8 P-Mentha Diene) against
Article in Pharmacognosy magazine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Bioactive Potential of Terpenes from Mediterranean Scrub Plants: A Review.Molecules (Basel, Switzerland) · 2025Review
- Topical application of (S)-(-)-limonene is as effective as phonophoresis for improving oxidative parameters of injured skeletal muscle in rats.Naunyn-Schmiedeberg's archives of pharmacology · 2020Article
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3 authors.
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Abstract
background
objectiveThe objective of this study was to study the growth-arresting activity of an indigenous Acmella essential oil (EO) ( MATERIALS AND
methodsThe EO was extracted from flowers of indigenous
resultsThe GC-MS analysis EO had inferred the presence of 7 number of major (≥2%) components. The component with highest peak area (%) was found to be 41.02. The HPLC-isolated fraction was identified as d-limonene (1,8 p-Mentha-diene) by FTIR and NMR. Qualitative and quantitative assays had suggested the growth inhibitory activity of Acmella EO and its component. Shrinkage, evacuation, cell wall puncture, and leakage of cellular constituents by the activity of Acmella oil and d-limonene were evidenced from optical, SEM, and TEM studies. The computer simulation had predicted the binding strengths of d-limonene and fluconazole with dermatophyte cell wall enzymes.
conclusionThere could have been synergistic action of all or some of compounds present in indigenous Acmella EO. SUMMARY: There was presence of seven number of (d-limonene, ocimene, β-myrcene, cyclohexene, 3-(1, 5-dimethyl-4-hexenyl)-6-methylene, β-caryophyllene, and β-sesquiphellandrene and β-phellandrene) major components in the indigenous Acmella essential oilThe d-limonene content was 41.02% in the indigenous oilThe antidermatophytic activity of Acmella essential oil could have been attributable to its chemotypes.
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