ArticlePharmacognosy magazine2017
Antioxidant Phytochemicals of
Article in Pharmacognosy magazine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 30 citations in OpenAlex.
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- Structure-Function Relationships and Health-Promoting Properties of the Main Nutraceuticals of the Cactus Pear (Molecules (Basel, Switzerland) · 2024Review
- Phytochemical profiling, antimicrobial, and antioxidant activities of hydroethanolic extracts of prickly pear (Food science & nutrition · 2023Article
- A Scoping Review on the Effects of Carotenoids and Flavonoids on Skin Damage Due to Ultraviolet Radiation.Nutrients · 2022Article
- Phenolic Compounds' Occurrence inMolecules (Basel, Switzerland) · 2022Review
- Chemical Characterization of Different Products from the TunisianFoods (Basel, Switzerland) · 2022Article
- Antidiarrheal and Cardio-Depressant Effects ofPlants (Basel, Switzerland) · 2021Article
- Article
- Opuntiol Prevents Photoaging of Mouse SkinOxidative medicine and cellular longevity · 2020Article
- Rapid, simple and potentially universal method for DNA extraction from Opuntia spp. fresh cladode tissues suitable for PCR amplification.Molecular biology reports · 2018Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background
objectivesPhytochemical analysis and antispasmodic effect of wild OFI cladodes were carried out. MATERIAL AND
methodsPolyphenols and Vitamin E occurrence, in antioxidant pool of OFI cladodes, were quantified by high-performance liquid chromatography. The antispasmodic effect of OFI cladodes was assessed in isolated rabbit smooth muscle tissues. The experiments were carried out with preparations of rabbit jejunum and uterus with the spontaneous contractile activity, to evaluate the effect of cumulative concentrations of the extract on basal tone, amplitude, and frequency of contractions.
resultsCatechin, quercetin, kaempferol, isorhamnetin and chlorogenic, ferulic, and p-coumaric acid were identified. α-, β-, and γ-tocopherols have been highlighted and α-tocopherol is the major component. OFI cladodes contain significant amount of polyphenols and tocopherols that are effective radical scavengers and inhibited ethanol 1,1-diphenyl-2-picrylhydrazyl formation by 50%. OFI cladodes caused a light inhibition of amplitude and frequency of spontaneous contractions and a marked decrease in muscle basal tone of rabbit jejunum preparations. On spontaneously contracting uterus preparations, the addition of increasing concentrations of cladode extract caused uterine muscle relaxation.
conclusionThe contraction of smooth muscle preparations depends on an increase in cytoplasmic free calcium ion concentration, which activates the contractile elements. The flavonoids may suppress the contractility of smooth myocytes, by an inhibition of availability of Ca SUMMARY:
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