Evidence map›Paper›PMID 29142322›Full record

ArticleScientific reports2017

Bilateral 5 Hz transcranial alternating current stimulation on fronto-temporal areas modulates resting-state EEG.

Aurora D'Atri, Claudia Romano, Maurizio Gorgoni, Serena Scarpelli, Valentina Alfonsi, Michele Ferrara, Fabio Ferlazzo, Paolo Maria Rossini, Luigi De Gennaro

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Aurora D'AtriDepartment of Psychology, University of Rome "Sapienza", Via dei Marsi 78, 00185, Rome, Italy.
Claudia RomanoDepartment of Psychology, University of Rome "Sapienza", Via dei Marsi 78, 00185, Rome, Italy.
Maurizio GorgoniDepartment of Psychology, University of Rome "Sapienza", Via dei Marsi 78, 00185, Rome, Italy.
Serena ScarpelliDepartment of Psychology, University of Rome "Sapienza", Via dei Marsi 78, 00185, Rome, Italy.ORCID 0000-0002-9260-7111
Valentina AlfonsiDepartment of Psychology, University of Rome "Sapienza", Via dei Marsi 78, 00185, Rome, Italy.
Michele FerraraDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio (Coppito 2), 67100 Coppito, L'Aquila, Italy.ORCID 0000-0003-2304-7576
Fabio FerlazzoDepartment of Psychology, University of Rome "Sapienza", Via dei Marsi 78, 00185, Rome, Italy.
Paolo Maria RossiniIRCCS San Raffaele Pisana, Via della Pisana 235, 00163, Rome, Italy.
Luigi De GennaroDepartment of Psychology, University of Rome "Sapienza", Via dei Marsi 78, 00185, Rome, Italy. luigi.degennaro@uniroma1.it.ORCID 0000-0003-3613-6631
Sapienza University of Rome · ITIRCCS Ospedale San Raffaele · ITUniversità Cattolica del Sacro Cuore · ITUniversity of L'Aquila · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhythmic non-invasive brain stimulations are promising tools to modulate brain activity by entraining neural oscillations in specific cortical networks. The aim of the study was to assess the possibility to influence the neural circuits of the wake-sleep transition in awake subjects via a bilateral transcranial alternating current stimulation at 5 Hz (θ-tACS) on fronto-temporal areas. 25 healthy volunteers participated in two within-subject sessions (θ-tACS and sham), one week apart and in counterbalanced order. We assessed the stimulation effects on cortical EEG activity (28 derivations) and self-reported sleepiness (Karolinska Sleepiness Scale). θ-tACS induced significant increases of the theta activity in temporo-parieto-occipital areas and centro-frontal increases in the alpha activity compared to sham but failed to induce any online effect on sleepiness. Since the total energy delivered in the sham condition was much less than in the active θ-tACS, the current data are unable to isolate the specific effect of entrained theta oscillatory activity per se on sleepiness scores. On this basis, we concluded that θ-tACS modulated theta and alpha EEG activity with a topography consistent with high sleep pressure conditions. However, no causal relation can be traced on the basis of the current results between these rhythms and changes on sleepiness.

Indexed as

Transcranial Direct Current StimulationAdolescentAdultElectroencephalographyFemaleHealthy VolunteersHumansMaleMembrane PotentialsNerve NetSleepinessTheta RhythmYoung Adult

Identifiers

PMID29142322
PMCPMC5688177
OpenAlexW2768046660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.