ArticleNeurologia medico-chirurgica2018
The Choroid Plexus of the Lateral Ventricle As the Origin of CSF Pulsation Is Questionable.
Article in Neurologia medico-chirurgica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Evaluating amplified magnetic resonance imaging as an input for computational fluid dynamics models of the cerebrospinal fluid.Interface focus · 2025Article
- Diffusion-derived intravoxel-incoherent motion anisotropy relates to CSF and blood flow.Magnetic resonance in medicine · 2025Article
- Low b-value Diffusion Tensor Imaging to Analyze the Dynamics of Cerebrospinal Fluid: Resolving Intravoxel Pseudorandom Motion into Ordered and Disordered Motions.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Four-dimensional flow MRI for quantitative assessment of cerebrospinal fluid dynamics: Status and opportunities.NMR in biomedicine · 2024Review
- Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies.Fluids and barriers of the CNS · 2022Review
- Evaluating the Effect of Arterial Pulsation on Cerebrospinal Fluid Motion in the Sylvian Fissure of Patients with Middle Cerebral Artery Occlusion Using Low b-value Diffusion-weighted Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2021Article
- The Pathogenesis Based on the Glymphatic System, Diagnosis, and Treatment of Idiopathic Normal Pressure Hydrocephalus.Clinical interventions in aging · 2021Review
- A Brief Overview of the Cerebrospinal Fluid System and Its Implications for Brain and Spinal Cord Diseases.Frontiers in human neuroscience · 2021Review
- Neurofluid Dynamics and the Glymphatic System: A Neuroimaging Perspective.Korean journal of radiology · 2020Review
- Optimal strategy for measuring intraventricular temperature using acceleration motion compensation diffusion-weighted imaging.Radiological physics and technology · 2020Article
- Simple Identification of Cerebrospinal Fluid Turbulent Motion Using a Dynamic Improved Motion-sensitized Driven-equilibrium Steady-state Free Precession Method Applied to Various Types of Cerebrospinal Fluid Motion Disturbance.Neurologia medico-chirurgica · 2020Article
- Upward movement of cerebrospinal fluid in obstructive hydrocephalus-revision of an old concept.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Changing the Currently Held Concept of Cerebrospinal Fluid Dynamics Based on Shared Findings of Cerebrospinal Fluid Motion in the Cranial Cavity Using Various Types of Magnetic Resonance Imaging Techniques.Neurologia medico-chirurgica · 2019Review
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The advent of magnetic resonance imaging (MRI) enables noninvasive measurement of cerebrospinal fluid (CSF) motion, and new information about CSF motion has now been acquired. The driving force of the CSF has long been thought to be choroid plexus (CP) pulsation, but to investigate whether this phenomenon actually occurs, CSF motion was observed in the ventricular system and subarachnoid space using MRI. Eleven healthy volunteers, ranging in age from 23 to 58 years, participated in this study. The MRI sequences used were four-dimensional phase-contrast (4D-PC) and time-spatial labeling inversion pulse (t-SLIP). The 4D-PC images included sagittal images in the cranial midline, coronal images focusing on the foramen of Monro (FOM), and oblique coronal images of the trigone to quantify CSF velocity and acceleration. These values were compared and analyzed as non-parametric data using the Kolmogorov-Smirnov test and the Mann-Whitney U test. 4D-PC showed that the median CSF velocity was significantly lower in the posterior part of the lateral ventricle than in other regions. The quantitative analysis of velocity and acceleration showed that they were decreased around the CP in the trigone. Image analysis of both velocity mapping and t-SLIP showed suppressed CSF motion around the CP in the trigone. These findings cast doubt on CP pulsation being the driving force for CSF motion.
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