Evidence map›Paper›PMID 29142131›Full record

ArticleJournal of virology2018

Single-Dose Trivalent VesiculoVax Vaccine Protects Macaques from Lethal Ebolavirus and Marburgvirus Challenge.

Demetrius Matassov, Chad E Mire, Theresa Latham, Joan B Geisbert, Rong Xu, Ayuko Ota-Setlik, Krystle N Agans, Dean J Kobs, Morgan Q S Wendling, Amanda Burnaugh and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Marburg Virus Medical Countermeasures.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Design of universal Ebola virus vaccine candidates via immunofocusing.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Article
  10. Design of universal Ebola virus vaccine candidatesbioRxiv : the preprint server for biology · 2023
    Article
  11. Review
  12. Natural history ofEmerging microbes & infections · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Demetrius MatassovDepartment of Virology and Vaccine Vectors, Profectus BioSciences Inc., Pearl River, New York, USA dmatassov@profectusbiosciences.com.
Chad E MireGalveston National Laboratory, University of Texas Medical Branch, Galveston, Texas, USA.
Theresa LathamDepartment of Virology and Vaccine Vectors, Profectus BioSciences Inc., Pearl River, New York, USA.
Joan B GeisbertGalveston National Laboratory, University of Texas Medical Branch, Galveston, Texas, USA.
Rong XuDepartment of Immunology, Profectus BioSciences Inc., Pearl River, New York, USA.
Ayuko Ota-SetlikDepartment of Immunology, Profectus BioSciences Inc., Pearl River, New York, USA.
Krystle N AgansGalveston National Laboratory, University of Texas Medical Branch, Galveston, Texas, USA.
Dean J KobsBattelle Memorial Institute, Columbus, Ohio, USA.
Morgan Q S WendlingBattelle Memorial Institute, Columbus, Ohio, USA.
Amanda BurnaughBattelle Memorial Institute, Columbus, Ohio, USA.
Thomas L RudgeBattelle Memorial Institute, Columbus, Ohio, USA.
Carol L SabourinBattelle Memorial Institute, Columbus, Ohio, USA.
Michael A EganDepartment of Immunology, Profectus BioSciences Inc., Pearl River, New York, USA.
David K ClarkeDepartment of Virology and Vaccine Vectors, Profectus BioSciences Inc., Pearl River, New York, USA.
Thomas W GeisbertGalveston National Laboratory, University of Texas Medical Branch, Galveston, Texas, USA.
John H EldridgeDepartment of Virology and Vaccine Vectors, Profectus BioSciences Inc., Pearl River, New York, USA.
Profectus Biosciences (United States) · USBattelle · USThe University of Texas Medical Branch at Galveston · US

Funding

Supplemental Research Project (SRP)U19AI109711 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI GEISBERT, THOMAS WILLIAM · 2014 to 2018
$26.6M
NIAID NIH HHS U19 AI109711
6 · The paper itself

Abstract

Previous studies demonstrated that a single intramuscular (i.m.) dose of an attenuated recombinant vesicular stomatitis virus (rVSV) vector (VesiculoVax vector platform; rVSV-N4CT1) expressing the glycoprotein (GP) from the Mayinga strain of

Indexed as

AnimalsAntibodies, ViralEbolavirusGlycoproteinsHemorrhagic Fever, EbolaImmunoglobulin GInjections, IntramuscularMacaca fascicularisMarburgvirusMarburg Virus DiseaseMiceVaccinationVaccines, AttenuatedVaccines, SyntheticVesiculovirusViral ProteinsAntibodies, ViralGlycoproteinsImmunoglobulin GVaccines, AttenuatedVaccines, SyntheticViral ProteinsViral VaccinesattenuationchallengeEbola virus vaccineglycoproteinMarburg virus vaccinenonhuman primatesprotectionrVSV vectortrivalentvaccine

Identifiers

PMID29142131
PMCPMC5774882
OpenAlexW2769289510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.