Evidence map›Paper›PMID 29142003›Full record

ReviewDiabetes care2018

Disparities in Environmental Exposures to Endocrine-Disrupting Chemicals and Diabetes Risk in Vulnerable Populations.

Daniel Ruiz, Marisol Becerra, Jyotsna S Jagai, Kerry Ard, Robert M Sargis

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07461857 (Minority-focused Environmental Health Education and Tracking), which is not on this map. Cited by 133 papers.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07461857 nacompletednot on this mapstarted 2025, after this paper: background citation

Minority-focused Environmental Health Education and Tracking (MEET) Pilot Study

TypeinterventionalSponsorMillion Marker Wellness, Inc.Ran2025 to 2026Enrolled151ConditionsEnvironmental ExposureArmsEducation curriculum
3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 220 citations in OpenAlex.

  1. Article
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  6. Observational
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  14. The Intersection of Socioeconomic and Environmental Factors in Aging: Insights from a Narrative Review.International journal of environmental research and public health · 2025
    Review
  15. Article
  16. Review
  17. Review
  18. Household Income, Maternal Allostatic Load During Pregnancy, and Offspring With Autism Spectrum Disorders.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  19. Article
  20. Article

73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Daniel RuizCommittee on Molecular Metabolism and Nutrition, University of Chicago, Chicago, IL.
Marisol BecerraCollege of Food, Agricultural, and Environmental Sciences, School of Environment and Natural Resources, Ohio State University, Columbus, OH.
Jyotsna S JagaiEnvironmental and Occupational Health Sciences Division, School of Public Health, University of Illinois at Chicago, Chicago, IL.
Kerry ArdCollege of Food, Agricultural, and Environmental Sciences, School of Environment and Natural Resources, Ohio State University, Columbus, OH.
Robert M SargisDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL rsargis@uic.edu.ORCID 0000-0001-7061-2983
The Ohio State University · USUniversity of Illinois Chicago · USUniversity of Chicago · US

Funding

Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI Matthew J Brady · 2013 to 2026
$20.9M
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)T32HD007009 · NICHD · UNIVERSITY OF CHICAGO · PI NANCY B SCHWARTZ · 1985 to 2026
$13.0M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI ELBERT S. HUANG · 2011 to 2026
$10.0M
University of Chicago Initiative for Maximizing Student Development (IMSD) - Renewal 01R25GM109439 · NIGMS · UNIVERSITY OF CHICAGO · PI SCHWARTZ, NANCY B · 2014 to 2023
$5.7M
NICHD NIH HHS T32 HD007009NIDDK NIH HHS P30 DK020595NIDDK NIH HHS P30 DK092949NIGMS NIH HHS R25 GM109439
6 · The paper itself

Abstract

Burgeoning epidemiological, animal, and cellular data link environmental endocrine-disrupting chemicals (EDCs) to metabolic dysfunction. Disproportionate exposure to diabetes-associated EDCs may be an underappreciated contributor to disparities in metabolic disease risk. The burden of diabetes is not uniformly borne by American society; rather, this disease disproportionately affects certain populations, including African Americans, Latinos, and low-income individuals. The purpose of this study was to review the evidence linking unequal exposures to EDCs with racial, ethnic, and socioeconomic diabetes disparities in the U.S.; discuss social forces promoting these disparities; and explore potential interventions. Articles examining the links between chemical exposures and metabolic disease were extracted from the U.S. National Library of Medicine for the period of 1966 to 3 December 2016. EDCs associated with diabetes in the literature were then searched for evidence of racial, ethnic, and socioeconomic exposure disparities. Among Latinos, African Americans, and low-income individuals, numerous studies have reported significantly higher exposures to diabetogenic EDCs, including polychlorinated biphenyls, organochlorine pesticides, multiple chemical constituents of air pollution, bisphenol A, and phthalates. This review reveals that unequal exposure to EDCs may be a novel contributor to diabetes disparities. Efforts to reduce the individual and societal burden of diabetes should include educating clinicians on environmental exposures that may increase disease risk, strategies to reduce those exposures, and social policies to address environmental inequality as a novel source of diabetes disparities.

Indexed as

Vulnerable PopulationsBenzhydryl CompoundsBisphenol A CompoundsDiabetes MellitusEndocrine DisruptorsEnvironmental ExposureEnvironmental PollutantsEthnicityHumansPesticidesPhenolsPhthalic AcidsPolychlorinated BiphenylsRisk FactorsSocioeconomic FactorsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEndocrine DisruptorsEnvironmental PollutantsPesticidesPhenolsphthalic acidPhthalic AcidsPolychlorinated Biphenyls

Identifiers

PMID29142003
PMCPMC5741159
OpenAlexW2768931026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.