Evidence map›Paper›PMID 29141978›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2017

Cobalamin Status from Pregnancy to Early Childhood: Lessons from Global Experience.

Rima Obeid, Michelle Murphy, Pol Solé-Navais, Chittaranjan Yajnik

Open access · bronzeAbstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Vitamin BInternational journal of molecular sciences · 2024
    Review
  9. Article
  10. Review
  11. The importance of vitamin BEuropean journal of nutrition · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Maternal Vitamin BNutrients · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Rima ObeidAarhus Institute of Advanced Studies, University of Aarhus, Aarhus, Denmark.
Michelle MurphyArea of Preventive Medicine and Public Health, Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Pere Virgili Institute for Health Research, Reus, Spain.
Pol Solé-NavaisArea of Preventive Medicine and Public Health, Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Pere Virgili Institute for Health Research, Reus, Spain.
Chittaranjan YajnikDiabetes Unit, King Edward Memorial Hospital Research Centre, Pune, India.
Institut de Recerca Biomèdica Catalunya Sud · ESAarhus University · DKKing Edward Memorial Hospital Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low cobalamin intake and status during pregnancy or lactation have been linked to adverse maternal and perinatal health outcomes, whereas low cobalamin status during early childhood is associated with impaired development in children. Women who begin pregnancy with depleted stores (low or very low plasma cobalamin) will give birth to depleted infants who are likely to develop deficiency symptoms during the first few weeks or months postpartum. Newly ingested cobalamin during pregnancy and lactation (from diet or supplements) is transferred to the child and is not likely to correct cobalamin status in depleted women. The prevalence of low cobalamin status is high especially in low-income settings or in populations with a low intake of animal products. Folate and cobalamin play interdependent roles in one-carbon metabolism. Although folic acid supplementation during early pregnancy is widely recommended and practiced, cobalamin supplementation during pregnancy and lactation has received little attention. Furthermore, the intake recommendations for pregnant and lactating women and in early life need reevaluation in the light of newly available evidence in the field.

Indexed as

AdultChild, PreschoolDeveloping CountriesFemaleHumansInfantInfant, NewbornLactationMaleMaternal Nutritional Physiological PhenomenaNutritional StatusPregnancyPregnancy ComplicationsVitamin B 12Vitamin B 12 DeficiencyVitamin B 12child developmentcobalamincord bloodinfantslactationpregnancyrecommended intakesupplementation

Identifiers

PMID29141978
PMCPMC5683008
OpenAlexW2774051640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.