Evidence map›Paper›PMID 29141956›Full record

ArticleBiology open2017

Rapid isolation and expansion of skin-derived precursor cells from human primary fibroblast cultures.

Leithe Budel, Karima Djabali

Abstract read
In one paragraph

Article in Biology open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  7. Functional hair follicle regeneration: an updated review.Signal transduction and targeted therapy · 2021
    Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Leithe BudelEpigenetics of Aging, Department of Dermatology, TUM school of Medicine, Technical University of Munich (TUM), 85748 Garching-Munich, Germany.
Karima DjabaliEpigenetics of Aging, Department of Dermatology, TUM school of Medicine, Technical University of Munich (TUM), 85748 Garching-Munich, Germany djabali@tum.de.ORCID http://orcid.org/0000-0003-4067-4977

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin-derived precursor (SKP) cells have self-renewal and multipotent abilities and are found in the dermis. SKP cells have been isolated previously from pre-established dermal fibroblast cultures. In these procedures, long-term culture and low yield remain the crucial aspects requiring improvement. In this study, we exposed pre-established dermal fibroblasts to 30-min acid stress prior to isolating SKP cells (termed pH-SKP) and compared the yield to the previously published trypsin- and no-stress methods. Spheroid formation was confirmed and analyzed at days 3, 5 and 7

Indexed as

Acidic stressAdult stem cellsHuman fibroblastMultipotentSkin-derived precursor cells

Identifiers

PMID29141956
PMCPMC5703604

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.