Evidence map›Paper›PMID 29141953›Full record

ArticleBiology open2017

Amyloid β42 peptide is toxic to non-neural cells in

Mercedes Arnés, Sergio Casas-Tintó, Anders Malmendal, Alberto Ferrús

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mercedes ArnésDept. of Molecular, Cellular and Developmental Neurobiology, Instituto Cajal, Avda. Doctor Arce, 37, 28002 Madrid, Spain.
Sergio Casas-TintóDept. of Molecular, Cellular and Developmental Neurobiology, Instituto Cajal, Avda. Doctor Arce, 37, 28002 Madrid, Spain.
Anders MalmendalBiochemistry and Structural Biology, Center for Molecular Protein Science, Department of Chemistry, Lund University, P.O. Box 124, SE-22100 Lund, Sweden aferrus@cajal.csic.es malmendal@gmail.com.ORCID http://orcid.org/0000-0002-8413-9717
Alberto FerrúsDept. of Molecular, Cellular and Developmental Neurobiology, Instituto Cajal, Avda. Doctor Arce, 37, 28002 Madrid, Spain aferrus@cajal.csic.es malmendal@gmail.com.ORCID http://orcid.org/0000-0002-0346-0489
Instituto Cajal · ESLund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human Aβ42 peptide is associated with Alzheimer's disease through its deleterious effects in neurons. Expressing the human peptide in adult

Indexed as

Amyloid βEpithelial cellsMetabolomicsNMRPI3KWingless

Identifiers

PMID29141953
PMCPMC5703620
OpenAlexW2768545935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.