ArticleThe Journal of biological chemistry2018
Munc13 proteins control regulated exocytosis in mast cells.
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Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
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Who cites it
23 citing papers in PubMed, 28 citations in OpenAlex.
- Molecular requirements for mammalian crinophagy highlight a key role for CaResearch square · 2025Article
- Fission yeast GPI inositol deacylase Bst1 regulates ER-Golgi transport and functions in late stages of cytokinesis.Molecular biology of the cell · 2025Article
- LRO biogenesis and function: what can we learn from mast cells?Frontiers in cell and developmental biology · 2025Review
- Vesicle trafficking and vesicle fusion: mechanisms, biological functions, and their implications for potential disease therapy.Molecular biomedicine · 2022Review
- A novel membrane complex is required for docking and regulated exocytosis of lysosome-related organelles in Tetrahymena thermophila.PLoS genetics · 2022Article
- In vivo Roles of Rab27 and Its Effectors in Exocytosis.Cell structure and function · 2021Review
- Early development and functional properties of tryptase/chymase double-positive mast cells from human pluripotent stem cells.Journal of molecular cell biology · 2021Article
- Probing the Diacylglycerol Binding Site of Presynaptic Munc13-1.Biochemistry · 2021Article
- Cytoskeletal Transport, Reorganization, and Fusion Regulation in Mast Cell-Stimulus Secretion Coupling.Frontiers in cell and developmental biology · 2021Review
- ELKS1 controls mast cell degranulation by regulating the transcription of Stxbp2 and Syntaxin 4 via Kdm2b stabilization.Science advances · 2020Article
- Lentiviral Gene Therapy for Familial Hemophagocytic Lymphohistiocytosis Type 3, Caused byHuman gene therapy · 2020Article
- Simultaneous Release of Multiple Vesicles from Rods Involves Synaptic Ribbons and Syntaxin 3B.Biophysical journal · 2020Article
- AlternativeFrontiers in immunology · 2020Article
- Article
- Munc13 Is a Molecular Target of Bryostatin 1.Biochemistry · 2019Article
- Munc18-2, but not Munc18-1 or Munc18-3, regulates platelet exocytosis, hemostasis, and thrombosis.The Journal of biological chemistry · 2019Article
- Article
- Syntaxin 3, but not syntaxin 4, is required for mast cell-regulated exocytosis, where it plays a primary role mediating compound exocytosis.The Journal of biological chemistry · 2019Article
- Anaphylactic Degranulation of Mast Cells: Focus on Compound Exocytosis.Journal of immunology research · 2019Review
- Roles of the fission yeast UNC-13/Munc13 protein Ync13 in late stages of cytokinesis.Molecular biology of the cell · 2018Article
Corrections and comments
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Authors and funding
20 authors at 3 institutions in 2 countries.
Elsa M RodarteDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León 64710, México.
Marco A RamosDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Alfredo J DavalosDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León 64710, México.
Daniel C MoreiraDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León 64710, México.
David S MorenoDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León 64710, México.
Eduardo I CardenasDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León 64710, México.
Alejandro I RodarteDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León 64710, México.
Youlia PetrovaDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Sofia MolinaDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León 64710, México.
Luis E RendonDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Elizabeth SanchezDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Keegan BreauxDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Alejandro TortorielloDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León 64710, México.
John ManlloDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Erika A GonzalezDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León 64710, México.
Michael J TuvimDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Burton F DickeyDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Alan R BurnsCollege of Optometry, University of Houston, Houston, Texas 77204.
Ruth HeidelbergerDepartment of Neurobiology and Anatomy, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas 77030.
Roberto AdachiDepartment of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030. Electronic address: radachi@mdanderson.org.
The University of Texas MD Anderson Cancer Center · USTecnológico de Monterrey · MXUniversity of Houston · US
Funding
Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8MResearch Programming ModuleP30EY007551 · NEI · UNIVERSITY OF HOUSTON · PI LAURA J. FRISHMAN · 1988 to 2026
$16.4MControlling the core airway mucin secretion machinery to prevent pathophysiologyR01HL129795 · NHLBI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DICKEY, BURTON F · 2015 to 2023
$3.8MOCULAR SURFACE INJURY: INFLAMMATORY CASCADE AND HEALING OF CORNEAL WOUNDSR01EY018239 · NEI · BAYLOR COLLEGE OF MEDICINE · PI BURNS, ALAN R, RUMBAUT, ROLANDO E · 2008 to 2020
$3.7MMechanism and pathophysiological significance of mast cell regulated exocytosisR01AI093533 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ADACHI, ROBERTO · 2011 to 2015
$2.1MMolecular Pathways Regulating Airway Goblet Cell Mucin SecretionR01HL097000 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVIS, C. WILLIAM, DICKEY, BURTON F · 2010 to 2013
$2.0MNCI NIH HHS P30 CA016672NEI NIH HHS P30 EY007551NEI NIH HHS R01 EY018239NHLBI NIH HHS R01 HL097000NHLBI NIH HHS R01 HL129795NIAID NIH HHS R01 AI093533
Abstract
Mast cells (MCs) are involved in host defenses against pathogens and inflammation. Stimulated MCs release substances stored in their granules via regulated exocytosis. In other cell types, Munc13 (mammalian homolog of
Indexed as
AnaphylaxisAnimalsDisease Models, AnimalExocytosisIntracellular Signaling Peptides and ProteinsMast CellsMembrane ProteinsMiceMice, Inbred C57BLMice, KnockoutNerve Tissue ProteinsProtein IsoformsProtein TransportIntracellular Signaling Peptides and ProteinsMembrane ProteinsNerve Tissue ProteinsProtein IsoformsUnc13a protein, mouseUnc13b protein, mouseUnc13d protein, mouseallergyanaphylaxisexocytosisimmunoglobulin E (IgE)mast cellMunc13SNARE proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.