Evidence map›Paper›PMID 29141852›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2018

Collagen Alignment as a Predictor of Recurrence after Ductal Carcinoma

Matthew W Conklin, Ronald E Gangnon, Brian L Sprague, Lisa Van Gemert, John M Hampton, Kevin W Eliceiri, Jeremy S Bredfeldt, Yuming Liu, Nuntida Surachaicharn, Polly A Newcomb and 3 more

Abstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 1 synthesis or guideline pooled it, 145 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Review
  6. Article
  7. The Duality of Collagens in Metastases of Solid Tumors.International journal of molecular sciences · 2025
    Review
  8. Review
  9. Polychromatic Polarization Microscopy Differentiates Collagen Fiber Signatures in Benign Pancreatic Tissue and Pancreatic Ductal Adenocarcinoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
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  17. Review
  18. Organoids technology in cancer research: from basic applications to advancedFrontiers in cell and developmental biology · 2025
    Review
  19. The Microenvironment in DCIS and Its Role in Disease Progression.Advances in experimental medicine and biology · 2025
    Review
  20. Review

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Matthew W ConklinDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin.
Ronald E GangnonCarbone Cancer Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Brian L SpragueDepartment of Surgery, University of Vermont, Burlington, Vermont.
Lisa Van GemertDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
John M HamptonCarbone Cancer Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Kevin W EliceiriCarbone Cancer Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Jeremy S BredfeldtLaboratory for Optical and Computational Instrumentation, University of Wisconsin-Madison, Madison, Wisconsin.
Yuming LiuLaboratory for Optical and Computational Instrumentation, University of Wisconsin-Madison, Madison, Wisconsin.
Nuntida SurachaicharnDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin.
Polly A NewcombFred Hutchinson Cancer Research Center, Seattle, Washington.
Andreas FriedlCarbone Cancer Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Patricia J Keely
Amy Trentham-DietzCarbone Cancer Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin. trentham@wisc.edu.
University of Wisconsin–Madison · USUniversity of Wisconsin Carbone Cancer Center · USUniversity of Wisconsin System · USFred Hutch Cancer Center · USUniversity of Vermont · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Nihal Ahmad · 1985 to 2026
$142.6M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Vermont Screening Process Documentation UnitU54CA163303 · NCI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SPRAGUE, BRIAN L · 2011 to 2017
$6.4M
RISK FACTORS AND BIOMARKERS FOR IN SITU BREAST CANCERR01CA067264 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI TRENTHAM-DIETZ, AMY · 1996 to 2013
$3.6M
Collagen structural changes as an early biomarker for breast carcinomaR01CA199996 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CONKLIN, MATTHEW W · 2015 to 2019
$2.2M
NCATS NIH HHS UL1 TR000427NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA067264NCI NIH HHS R01 CA199996NCI NIH HHS U54 CA163303
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease ProgressionNeoplasm Recurrence, LocalAdultAgedAnalysis of VarianceBiomarkers, TumorBreast NeoplasmsCarcinoma, Intraductal, NoninfiltratingCollagenDisease-Free SurvivalFemaleHumansLongitudinal StudiesMiddle AgedReceptors, EstrogenReceptors, ProgesteroneBiomarkers, TumorCollagenReceptors, EstrogenReceptors, ProgesteroneSDC1 protein, humanSyndecan-1

Identifiers

PMID29141852
PMCPMC5809285
OpenAlexW2769836808

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.