Evidence map›Paper›PMID 29141760›Full record

ArticleThe American journal of tropical medicine and hygiene2018

Glucose-6-Phosphate Dehydrogenase Deficiency Genetic Variants in Malaria Patients in Southwestern Ethiopia.

Tamar E Carter, Seleshi Kebede Mekonnen, Karen Lopez, Victoria Bonnell, Lambodhar Damodaran, Abraham Aseffa, Daniel A Janies

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. No G6PD A- (G202A) variant detected amongMalariaWorld journal · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Tamar E CarterDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, North Carolina.
Seleshi Kebede MekonnenArmauer Hansen Research Institute, Addis Ababa, Ethiopia.
Karen LopezDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, North Carolina.
Victoria BonnellDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, North Carolina.
Lambodhar DamodaranDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, North Carolina.
Abraham AseffaArmauer Hansen Research Institute, Addis Ababa, Ethiopia.
Daniel A JaniesDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, North Carolina.
University of North Carolina at Charlotte · USArmauer Hansen Research Institute · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked erythrocyte enzyme disorder with relevance to malaria treatment policy. Treatment with the antimalarial primaquine can result in hemolytic anemia in G6PD-deficient patients. With increased interest in primaquine use, it is important to identify G6PD variants in Ethiopia to inform malaria treatment policy. In the present study, mutations in the

Indexed as

EthiopiaFemaleGlucosephosphate Dehydrogenase DeficiencyHumansMalaria, FalciparumMalaria, VivaxMalePolymerase Chain ReactionPolymorphism, Single NucleotideSex Factors

Identifiers

PMID29141760
PMCPMC5928732
OpenAlexW2765447183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.