Evidence map›Paper›PMID 29141757›Full record

ArticleThe American journal of tropical medicine and hygiene2018

Protein-Specific Features Associated with Variability in Human Antibody Responses to

Eugene W Liu, Jeff Skinner, Tuan M Tran, Krishan Kumar, David L Narum, Aarti Jain, Aissata Ongoiba, Boubacar Traoré, Philip L Felgner, Peter D Crompton

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Identification of Oocyst-DrivenMicroorganisms · 2021
    Review
  3. Article
  4. Article
  5. Naturally Acquired Humoral Immunity AgainstFrontiers in immunology · 2020
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Eugene W LiuLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland.
Jeff SkinnerLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland.
Tuan M TranDivision of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
Krishan KumarLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
David L NarumLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Aarti JainUniversity of California, Irvine, Irvine, California.
Aissata OngoibaMali International Center of Excellence in Research, University of Sciences,Techniques and Technologies of Bamako, Bamako, Mali.
Boubacar TraoréMali International Center of Excellence in Research, University of Sciences,Techniques and Technologies of Bamako, Bamako, Mali.
Philip L FelgnerUniversity of California, Irvine, Irvine, California.
Peter D CromptonLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland.

Funding

Mechanisms of naturally-acquired immunity to malaria and clinical trials of anti-malaria monoclonal antibodiesZIAAI001155 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CROMPTON, PETER · 2011 to 2025
$30.9M
TransmissionU19AI089686 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ZIMMERMAN, PETER A. · 2010 to 2016
$9.9M
Predicting naturally acquired humoral immunity against malariaR01AI095916 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI FELGNER, PHILIP LOUIS · 2012 to 2016
$2.1M
NIAID NIH HHS R01 AI095916NIAID NIH HHS U19 AI089686
6 · The paper itself

Abstract

The magnitude of antibody responses varies across the individual proteins that constitute any given microorganism, both in the context of natural infection and vaccination with attenuated or inactivated pathogens. The protein-specific factors underlying this variability are poorly understood. In 267 individuals exposed to intense seasonal malaria, we examined the relationship between immunoglobulin G (IgG) responses to 861

Indexed as

AdolescentAdultAge FactorsAntibodies, ProtozoanAntibody FormationAntigens, ProtozoanChildChild, PreschoolCross ReactionsFemaleHumansImmunoglobulin GInfantMalaria, FalciparumMaleMaliAntibodies, ProtozoanAntigens, ProtozoanImmunoglobulin GProtozoan Proteins

Identifiers

PMID29141757
PMCPMC5928716

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.