Evidence map›Paper›PMID 29141726›Full record

ArticleThe American journal of tropical medicine and hygiene2018

Status of Insecticide Resistance in Papua New Guinea: An Update from Nation-Wide Monitoring of

Gussy Koimbu, Cyrille Czeher, Michelle Katusele, Muker Sakur, Lemen Kilepak, Anthony Tandrapah, Manuel W Hetzel, Justin Pulford, Leanne Robinson, Stephan Karl

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Gussy KoimbuPapua New Guinea Institute of Medical Research, Madang, Madang Province, Papua New Guinea.
Cyrille CzeherPapua New Guinea Institute of Medical Research, Madang, Madang Province, Papua New Guinea.
Michelle KatuselePapua New Guinea Institute of Medical Research, Madang, Madang Province, Papua New Guinea.
Muker SakurPapua New Guinea Institute of Medical Research, Madang, Madang Province, Papua New Guinea.
Lemen KilepakPapua New Guinea Institute of Medical Research, Madang, Madang Province, Papua New Guinea.
Anthony TandrapahPapua New Guinea Institute of Medical Research, Madang, Madang Province, Papua New Guinea.
Manuel W HetzelUniversity of Basel, Basel, Switzerland.
Justin PulfordLiverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom.
Leanne RobinsonUniversity of Melbourne, Melbourne, Australia.
Stephan KarlPapua New Guinea Institute of Medical Research, Madang, Madang Province, Papua New Guinea.
Papua New Guinea Institute of Medical Research · PGLiverpool School of Tropical Medicine · GBSwiss Tropical and Public Health Institute · CHWalter and Eliza Hall Institute of Medical Research · AU

Funding

TransmissionU19AI089686 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ZIMMERMAN, PETER A. · 2010 to 2016
$9.9M
NIAID NIH HHS U19 AI089686
6 · The paper itself

Abstract

Insecticide resistance (IR) monitoring is an important component of vector-borne disease control. The last assessment of IR in Papua New Guinea (PNG) was conducted in 2010. Since then, vector populations have been exposed to higher levels of pyrethroids with the continued nation-wide distribution of insecticide-treated nets. Here, we provide an update on phenotypic IR in four highly malaria-endemic areas of PNG. IR against deltamethrin, lambda-cyhalothrin, and dichlorodiphenyltrichloroethane was assessed using World Health Organization bioassays. A total of 108 bioassays for each insecticide were conducted screening 2,290 adult female anopheline mosquitoes. No phenotypic resistance was observed. Bioassay parameters agreed well with those observed in other studies that used the same assays and insecticides. These results indicate that the three tested insecticides are still universally effective in PNG. Continued IR monitoring (every 1-2 years) in PNG is recommended to detect reduced susceptibility early and adjust guidelines to prevent widespread resistance.

Indexed as

AnophelesInsecticide ResistanceAnimalsBiological AssayDDTFemaleMosquito ControlNitrilesPapua New GuineaPhenotypePyrethrinscyhalothrinDDTdecamethrinNitrilesPyrethrins

Identifiers

PMID29141726
PMCPMC5928719
OpenAlexW2768544441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.