Evidence map›Paper›PMID 29141723›Full record

ArticleThe American journal of tropical medicine and hygiene2018

Emergence, Epidemiology, and Transmission Dynamics of 2009 Pandemic A/H1N1 Influenza in Kampala, Uganda, 2009-2015.

Matthew J Cummings, Barnabas Bakamutumaho, Wan Yang, Joseph F Wamala, John Kayiwa, Nicholas Owor, Barbara Namagambo, Timothy Byaruhanga, Allison Wolf, Julius J Lutwama and 2 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Matthew J CummingsDivision of Pulmonary, Allergy, and Critical Care Medicine, Columbia University Medical Center, New York.
Barnabas BakamutumahoNational Influenza Center, Uganda Virus Research Institute, Entebbe, Uganda.
Wan YangDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York.
Joseph F WamalaSouth Sudan Country Office, World Health Organization, Juba, South Sudan.
John KayiwaNational Influenza Center, Uganda Virus Research Institute, Entebbe, Uganda.
Nicholas OworNational Influenza Center, Uganda Virus Research Institute, Entebbe, Uganda.
Barbara NamagamboNational Influenza Center, Uganda Virus Research Institute, Entebbe, Uganda.
Timothy ByaruhangaNational Influenza Center, Uganda Virus Research Institute, Entebbe, Uganda.
Allison WolfDivision of Pulmonary, Allergy, and Critical Care Medicine, Columbia University Medical Center, New York.
Julius J LutwamaNational Influenza Center, Uganda Virus Research Institute, Entebbe, Uganda.
Jeffrey ShamanDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York.
Max R O'DonnellDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.

Funding

Biomarker for XDR-TB Treatment Response and Drug Resistance in HIV Endemic AreaK23AI098479 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI O'DONNELL, MAX · 2012 to 2016
$669k
NIAID NIH HHS K23 AI098479World Health Organization 001
6 · The paper itself

Abstract

In sub-Saharan Africa, little is known about the epidemiology of pandemic-prone influenza viruses in urban settings. Using data from a prospective sentinel surveillance network, we characterized the emergence, epidemiology, and transmission dynamics of 2009 pandemic A/H1N1 influenza (H1N1pdm09) in Kampala, Uganda. After virus introduction via international air travel from England in June 2009, we estimated the basic reproductive number in Kampala to be 1.06-1.13, corresponding to attack rates of 12-22%. We subsequently identified 613 cases of influenza in Kampala from 2009 to 2015, of which 191 (31.2%) were infected with H1N1pdm09. Patients infected with H1N1pdm09 were more likely to be older adult (ages 35-64) males with illness onset during rainy season months. Urban settings in sub-Saharan Africa are vulnerable to importation and intense transmission of pandemic-prone influenza viruses. Enhanced surveillance and influenza pandemic preparedness in these settings is needed.

Indexed as

Influenza A Virus, H1N1 SubtypeAdolescentAdultAge FactorsChildChild, PreschoolFemaleHumansInfantInfluenza, HumanMaleMiddle AgedPandemicsRisk FactorsSeasonsSentinel Surveillance

Identifiers

PMID29141723
PMCPMC5928728

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.