Evidence map›Paper›PMID 29141712›Full record

Trial reportThe American journal of tropical medicine and hygiene2017

Clinical Outcomes during Treatment Interruptions in Human Immunodeficiency Virus-Hepatitis B Virus Co-infected Patients from Sub-Saharan Africa.

Anders Boyd, Laura Houghtaling, Raoul Moh, Mariama Abdou Chekaraou, Delphine Gabillard, Serge Paul Eholié, Xavier Anglaret, Fabien Zoulim, Christine Danel, Karine Lacombe and 1 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Research gaps in viral hepatitis.Journal of the International AIDS Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anders BoydINSERM, UMR_S1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France.
Laura HoughtalingDivision of Epidemiology, University of Minnesota, Minneapolis, Minnesota.
Raoul MohProgramme PAC-CI, ANRS Research Site, Treichville University Hospital, Abidjan, Côte d'Ivoire.
Mariama Abdou ChekaraouCentre de Recherche sur le Cancer de Lyon, Equipes 15 et 16, INSERM, Unité 1052, CNRS, UMR 5286, Lyon, France.
Delphine GabillardUniversity of Bordeaux, ISPED, Bordeaux, France.
Serge Paul EholiéMedical School, University Felix Houphouet Boigny, Abidjan, Côte d'Ivoire.
Xavier AnglaretUniversity of Bordeaux, ISPED, Bordeaux, France.
Fabien ZoulimCentre de Recherche sur le Cancer de Lyon, Equipes 15 et 16, INSERM, Unité 1052, CNRS, UMR 5286, Lyon, France.
Christine DanelUniversity of Bordeaux, ISPED, Bordeaux, France.
Karine LacombeSorbonne Universités, INSERM, UPMC Univ Paris 06, Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Paris, France.
For The Anrs Trivacan And Anrs VarBVA Studies

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antiretroviral treatment (ART) interruptions increase the risk of severe morbidity/mortality in human immunodeficiency virus (HIV)-infected individuals from subSaharan Africa. We aimed to determine whether the risk is further increased among HIV-hepatitis B virus (HBV) co-infected patients in this setting. In this sub-analysis of a randomized-control trial, 632 participants from Côte d'Ivoire randomized to receive continuous-ART (C-ART), structured ART interruptions of 2-months off, 4-months on (2/4-ART), and CD4-guided ART interruptions (CD4GT, interruption at 350/mm

Indexed as

Africa South of the SaharaAntiretroviral Therapy, Highly ActiveCoinfectionCote d'IvoireDNA, ViralFollow-Up StudiesHepatitis BHepatitis B Surface AntigensHepatitis B virusHIV-1HIV InfectionsHumansIncidenceMorbidityTreatment OutcomeVirus ReplicationDNA, ViralHepatitis B Surface Antigens

Identifiers

PMID29141712
PMCPMC5805028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.