ReviewSeminars in cell & developmental biology2019
Motor neuron migration and positioning mechanisms: New roles for guidance cues.
Review in Seminars in cell & developmental biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Co-option and innovation in neural crest evolution.Science advances · 2026Review
- Cell alignment on novel polymeric micro-hollow fiber membranes for neural and musculoskeletal tissue engineering.Cell and tissue research · 2026Article
- Defining spinal motor neuron subtypes across development: from embryonic specification to postnatal maturation.Frontiers in cellular neuroscience · 2026Review
- Evolution and development of extraocular motor neurons, nerves and muscles in vertebrates.Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft · 2024Review
- Regenerating the Injured Spinal Cord at the Chronic Phase by Engineered iPSCs-Derived 3D Neuronal Networks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Smoothened overexpression causes trochlear motoneurons to reroute and innervate ipsilateral eyes.Cell and tissue research · 2021Article
- Temporally regulated cell migration is sensitive to variation in body size.Development (Cambridge, England) · 2021Article
- Sequencing analysis of matrix metalloproteinase 7-induced genetic changes in Schwann cells.Neural regeneration research · 2020Article
- TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation.Cell reports · 2020Article
- Review
- Slit/Robo signals prevent spinal motor neuron emigration by organizing the spinal cord basement membrane.Developmental biology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Motor neurons differentiate from progenitor cells and cluster as motor nuclei, settling next to the floor plate in the brain stem and spinal cord. Although precise positioning of motor neurons is critical for their functional input and output, the molecular mechanisms that guide motor neurons to their proper positions remain poorly understood. Here, we review recent evidence of motor neuron positioning mechanisms, highlighting situations in which motor neuron cell bodies can migrate, and experiments that show that their migration is regulated by axon guidance cues. The view that emerges is that motor neurons are actively trapped or restricted in static positions, as the cells balance a push in the dorsal direction by repulsive Slit/Robo cues and a pull in the ventral direction by attractive Netrin-1/DCC cues. These new functions of guidance cues are necessary fine-tuning to set up patterns of motor neurons at their proper positions in the neural tube during embryogenesis.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.