Evidence map›Paper›PMID 29140890›Full record

ReviewSexually transmitted diseases2017

Selecting an HIV Test: A Narrative Review for Clinicians and Researchers.

Christopher B Hurt, Julie A E Nelson, Lisa B Hightow-Weidman, William C Miller

Open access · greenAbstract readReview
In one paragraph

Review in Sexually transmitted diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
  2. CD169 expression of CD14BMC infectious diseases · 2026
    Article
  3. Article
  4. Drug and therapeutic intravaginal delivery targeting diseases in the female reproductive tract: A mathematical modeling perspective.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Review
  5. Article
  6. Barriers to Rapid Enrollment and ART Initiation Among U.S. HIV Care Facilities.Journal of acquired immune deficiency syndromes (1999) · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. HIV infection.Nature reviews. Disease primers · 2023
    Review
  13. HIV and Drug-Resistant Subtypes.Microorganisms · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Neurologic Complications of Acute HIV Infection.Current treatment options in infectious diseases · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christopher B HurtFrom the *Institute for Global Health and Infectious Diseases, †Behavior and Technology Lab, and ‡Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC; and §Division of Epidemiology, College of Public Health, Ohio State University, Columbus, OH.
Julie A E Nelson
Lisa B Hightow-Weidman
William C Miller
University of North Carolina at Chapel Hill · US

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Option B+: ART Safety and Durability during First and Subsequent PregnanciesR01HD080485 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HOSSEINIPOUR, MINA CHRISTINE · 2014 to 2019
$3.9M
Reaching Unaware Sexual and Social Contacts to Interrupt Ongoing HIV TransmissionR01AI114320 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MILLER, WILLIAM C, POWERS, KIMBERLY A · 2014 to 2017
$2.5M
Home-Collected Blood Spots to Increase HIV Test Frequency among Young Black MSMK23MH099941 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HURT, CHRISTOPHER BROWNING · 2013 to 2017
$837k
Improving the HIV testing experience for YMSMR43HD088319 · NICHD · VIRTUALLY BETTER, INC. · PI ADAMS LARSEN, MARGO, HIGHTOW-WEIDMAN, LISA B · 2016 to 2016
$225k
NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI114320NICHD NIH HHS R01 HD080485NICHD NIH HHS R43 HD088319NIMH NIH HHS K23 MH099941
6 · The paper itself

Abstract

Given the many options available, selecting an HIV test for a particular clinical or research setting can be daunting. Making an informed decision requires an assessment of the likelihood of acute infection in the test population and an understanding of key aspects of the tests themselves. The ability of individual tests to reliably detect HIV infection depends on the target(s) being detected, when they can be expected to be present after infection, and the concentration of stable target in test specimens, all of which are explained by the virologic and serologic events after infection. The purpose of this article is to review the timeline of HIV infection, nomenclature, and characteristics of different tests; compare point-of-care and laboratory-based tests; discuss the impact of different specimens on test performance; and provide practical advice to help clinicians and researchers new to the field select a test that best suits their needs.

Indexed as

Point-of-Care TestingAlgorithmsClinical Laboratory TechniquesHIVHIV InfectionsHumansSerologic TestsSpecimen Handling

Identifiers

PMID29140890
PMCPMC5718364
OpenAlexW2754806768

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.