ReviewCurrent opinion in ophthalmology2018
Drop instillation and glaucoma.
Review in Current opinion in ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 73 citations in OpenAlex.
- The effects of self-video feedback on the eyedrop instillation techniques of glaucoma patients: a prospective randomized controlled trial.International ophthalmology · 2024Trial
- Investigation of visual and physical factors associated with inadequate instillation of eyedrops among patients with glaucoma.PloS one · 2021Trial
- Association of Comprehensive Geriatric Assessment with Knowledge- and Technique-Related Eye Drop Adherence Problems in Glaucoma Assessed Using the Shimane University Glaucoma Eye Drop Adherence Questionnaire.Journal of clinical medicine · 2026Article
- Clinical Microbial Contamination of Multidose Brimonidine: A Prospective Comparison of Benzalkonium Chloride and Purite® Preservatives.Journal of ophthalmology · 2026Article
- Patient and Neighborhood Factors Influencing Participation in a Personalized Glaucoma Coaching Program.Ophthalmic research · 2026Article
- Assessment of eye drop instillation technique in patients with glaucoma: a hospital-based cross-sectional study in Eastern China.BMC ophthalmology · 2025Observational
- Effectiveness of a Newly Developed Instillation Aid for Unit-Dose Ophthalmic Solutions.Journal of clinical medicine · 2025Article
- Development of Rifampicin Eye Drops for the Treatment of Exudative Age-Related Macular Degeneration.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Article
- Two-Year Post-Market Surveillance of iStentClinical ophthalmology (Auckland, N.Z.) · 2025Article
- Evaluating and Managing the Microbial Contamination of Eye Drops: A Two-Phase Hospital-Based Study.Pharmaceutics · 2024Article
- Persistence with medical glaucoma therapy in newly diagnosed patients.Medical hypothesis, discovery & innovation ophthalmology journal · 2024Article
- Development and Testing of a Multi-Component Intervention to Improve Medication Literacy in Glaucoma Patients.Patient preference and adherence · 2024Article
- Estimation of Topical Glaucoma Medication Over-Prescription and Its Associated Factors.Journal of clinical medicine · 2023Article
- Challenging the "Topical Medications-First" Approach to Glaucoma: A Treatment Paradigm in Evolution.Ophthalmology and therapy · 2023Article
- Factors Associated with Topical Medication Instillation Failure in Glaucoma: VRAMS-QPiG Study.Advances in therapy · 2023Observational
- Article
- Intereye comparison of visual field progression in eyes with open-angle glaucoma.Japanese journal of ophthalmology · 2023Observational
- A Review on Dry Eye Disease Treatment: Recent Progress, Diagnostics, and Future Perspectives.Pharmaceutics · 2023Review
- Intraocular nano-microscale drug delivery systems for glaucoma treatment: design strategies and recent progress.Journal of nanobiotechnology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewTo describe the current state of knowledge regarding glaucoma patients' eye drop technique, interventions attempting to improve eye drop technique, and methods for assessing eye drop technique. RECENT
findingsIn observational studies, between 18.2 and 80% of patients contaminate their eye drop bottle by touching their eye or face, 11.3-60.6% do not instill exactly one drop, and 6.8-37.3% miss the eye with the drop. Factors significantly associated with poorer technique include older age, lack of instruction on eye drop technique, female sex, arthritis, more severe visual field defect, lack of positive reinforcement to take eye drops, lower educational level, low self-efficacy, and being seen at a clinic rather than a private practice. Among intervention studies, four of five studies using a mechanical device and three of four studies using educational interventions to improve technique showed positive results, but none of the studies were randomized controlled trials. SUMMARY: Poor eye drop technique is a significant impediment to achieving good control of intraocular pressure in glaucoma. Both mechanical device interventions and educational interventions offer promise to improve patients' technique, but studies with stronger designs need to be done followed by introduction into clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.