Evidence map›Paper›PMID 29140270›Full record

ReviewMarine drugs2017

The Oxepane Motif in Marine Drugs.

Héctor Barbero, Carlos Díez-Poza, Asunción Barbero

Abstract readReview
In one paragraph

Review in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023
    Review
  9. Review
  10. Article
  11. Review
  12. Structure-Activity Relationship of Cytotoxic Natural Products from Indonesian Marine Sponges.Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Héctor BarberoGIR MIOMeT, IU CINQUIMA/Inorganic Chemistry, University of Valladolid, Campus Miguel Delibes, 47011 Valladolid, Spain. hector.barbero@uva.es.
Carlos Díez-PozaDepartment of Organic Chemistry, University of Valladolid, Campus Miguel Delibes, 47011 Valladolid, Spain. carlos.diez@alumnos.uva.es.
Asunción BarberoDepartment of Organic Chemistry, University of Valladolid, Campus Miguel Delibes, 47011 Valladolid, Spain. asuncion.barbero@uva.es.ORCID 0000-0001-6825-7775

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oceans have shown to be a remarkable source of natural products. The biological properties of many of these compounds have helped to produce great advances in medicinal chemistry. Within them, marine natural products containing an oxepanyl ring are present in a great variety of algae, sponges, fungus and corals and show very important biological activities, many of them possessing remarkable cytotoxic properties against a wide range of cancer cell lines. Their rich chemical structures have attracted the attention of many researchers who have reported interesting synthetic approaches to these targets. This review covers the most prominent examples of these types of compounds, focusing the discussion on the isolation, structure determination, medicinal properties and total synthesis of these products.

Indexed as

AnimalsBiological ProductsHumansMarine BiologyBiological Productsbiological activitymarine drugsoxepanestotal synthesis

Identifiers

PMID29140270
PMCPMC5706050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.