Evidence map›Paper›PMID 29139104›Full record

ArticleAmerican journal of physical anthropology2018

Ancestry and dental development: A geographic and genetic perspective.

Brunilda Dhamo, Lea Kragt, Olja Grgic, Strahinja Vucic, Carolina Medina-Gomez, Fernando Rivadeneira, Vincent W V Jaddoe, Eppo B Wolvius, Edwin M Ongkosuwito

Open access · hybridAbstract read
In one paragraph

Article in American journal of physical anthropology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Ancestry estimation: Methodological evolution and forensic implications.Forensic science, medicine, and pathology · 2026
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  18. Ancestry and dental development: A geographic and genetic perspective.American journal of physical anthropology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Brunilda DhamoThe Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus University Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0002-5537-067X
Lea KragtThe Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus University Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0002-4223-429X
Olja GrgicThe Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Strahinja VucicThe Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus University Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0003-3352-3900
Carolina Medina-GomezThe Generation R Study Group, Erasmus University Medical Centre, the Netherlands.
Fernando RivadeneiraThe Generation R Study Group, Erasmus University Medical Centre, the Netherlands.ORCID 0000-0001-9435-9441
Vincent W V JaddoeThe Generation R Study Group, Erasmus University Medical Centre, the Netherlands.
Eppo B WolviusThe Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Edwin M OngkosuwitoThe Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus University Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0001-9250-027X
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn this study, we investigated the influence of ancestry on dental development in the Generation R Study.

methodsInformation on geographic ancestry was available in 3,600 children (1,810 boys and 1,790 girls, mean age 9.81 ± 0.35 years) and information about genetic ancestry was available in 2,786 children (1,387 boys and 1,399 girls, mean age 9.82 ± 0.34 years). Dental development was assessed in all children using the Demirjian method. The associations of geographic ancestry (Cape Verdean, Moroccan, Turkish, Dutch Antillean, Surinamese Creole and Surinamese Hindustani vs Dutch as the reference group) and genetic content of ancestry (European, African or Asian) with dental development was analyzed using linear regression models.

resultsIn a geographic perspective of ancestry, Moroccan (β = 0.18; 95% CI: 0.07, 0.28), Turkish (β = 0.22; 95% CI: 0.12, 0.32), Dutch Antillean (β = 0.27; 95% CI: 0.12, 0.41), and Surinamese Creole (β = 0.16; 95% CI: 0.03, 0.30) preceded Dutch children in dental development. Moreover, in a genetic perspective of ancestry, a higher proportion of European ancestry was associated with decelerated dental development (β = -0.32; 95% CI: -.44, -.20). In contrast, a higher proportion of African ancestry (β = 0.29; 95% CI: 0.16, 0.43) and a higher proportion of Asian ancestry (β = 0.28; 95% CI: 0.09, 0.48) were associated with accelerated dental development. When investigating only European children, these effect estimates increased to twice as large in absolute value.

conclusionBased on a geographic and genetic perspective, differences in dental development exist in a population of heterogeneous ancestry and should be considered when describing the physiological growth in children.

Indexed as

Anthropology, PhysicalChildFemaleHumansLinear ModelsMaleMoroccoNetherlandsOdontogenesisRacial GroupsSurinameTurkeydental agegenesgeographymaturationorigintooth

Identifiers

PMID29139104
PMCPMC5813218
OpenAlexW2769158747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.