Evidence map›Paper›PMID 29138972›Full record

ArticlePlanta2018

Stable isotope labeling and 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside biosynthetic pathway characterization in Fallopia multiflora.

Wanxia Xia, Wen Rui, Wei Zhao, Shujing Sheng, Lei Lei, Yifan Feng, Shujin Zhao

Abstract read
PubMed Publisher
In one paragraph

Article in Planta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. The first chromosome-levelHorticulture research · 2023
    Article
  2. Article
  3. Article
  4. 2,3,5,4'-Tetrahydroxy-stilbene-2-Pharmaceutical biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Wanxia XiaSchool of Bioscience and Bioengineering, South China University of Technology, Guangzhou, 510006, People's Republic of China.
Wen RuiCentre Laboratory, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Wei ZhaoSchool of Bioscience and Bioengineering, South China University of Technology, Guangzhou, 510006, People's Republic of China.
Shujing ShengCollege of Biology and Food Engineering, Guangdong University of Education, Guangzhou, 510303, People's Republic of China.
Lei LeiSchool of Bioscience and Bioengineering, South China University of Technology, Guangzhou, 510006, People's Republic of China.
Yifan FengCentre Laboratory, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Shujin ZhaoSchool of Bioscience and Bioengineering, South China University of Technology, Guangzhou, 510006, People's Republic of China. gzzsjzhs@163.com.
Bioscience (China) · CNGuangdong Pharmaceutical University · CNGeneral Hospital of Guangzhou Military Command · CNGuangdong University of Education · CNSouth China University of Technology · CN

Funding

Guangzhou Science Technology and Innovation Commission 201707010459National Natural Science Foundation of China (CN) 31600236Natural Science Foundation of Guangdong Province (CN) 10151001002000012
6 · The paper itself

Abstract

MAIN

conclusionThe THSG biosynthetic pathway in F. multiflora was characterized, and enzymatic activities responsible for the resveratrol synthesis, hydroxylation, and glycosylation reactions involved in THSG biosynthesis were confirmed in vitro. The biosynthetic origin of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside (THSG) and the enzymes involved in THSG biosynthesis in Fallopia multiflora were studied using stable isotope labeling and biocatalytic methods. UPLC-MS-based analyses were used to unravel the isotopologue composition of the biosynthetic intermediates and products, as well as to detect the products of the enzyme assay experiments. In this study,

Indexed as

Metabolic Networks and PathwaysFallopia multifloraGlucosidesGlycosylationHydroxylationIsotope LabelingResveratrolStilbenes2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucopyranosideGlucosidesResveratrolStilbenes13C-labeled precursorEnzyme assayGlycosylationHydroxylationResveratrol synthaseUPLC-MS

Identifiers

PMID29138972
OpenAlexW2768622007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.