Evidence map›Paper›PMID 29138954›Full record

ArticleInflammopharmacology2018

Identification of compounds from Palicourea rigida leaves with topical anti-inflammatory potential using experimental models.

Rafael P Pinheiro, Muiara A Moraes, Bruna C S Santos, Rodrigo L Fabri, Glauciemar Del-Vechio-Vieira, Célia H Yamamoto, Ana Lúcia S M Araújo, Aílson L A Araújo, Orlando V Sousa

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Toxic Potential of Cerrado Plants on Different Organisms.International journal of molecular sciences · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rafael P PinheiroDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Campus Universitário, São Pedro, Minas Gerais, 36036-900, Brazil.
Muiara A MoraesDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Campus Universitário, São Pedro, Minas Gerais, 36036-900, Brazil.
Bruna C S SantosDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Campus Universitário, São Pedro, Minas Gerais, 36036-900, Brazil.
Rodrigo L FabriDepartment of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Campus Universitário, Juiz de Fora, Minas Gerais, 36036-330, Brazil.
Glauciemar Del-Vechio-VieiraDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Campus Universitário, São Pedro, Minas Gerais, 36036-900, Brazil.
Célia H YamamotoDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Campus Universitário, São Pedro, Minas Gerais, 36036-900, Brazil.
Ana Lúcia S M AraújoDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Campus Universitário, São Pedro, Minas Gerais, 36036-900, Brazil.
Aílson L A AraújoDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Campus Universitário, São Pedro, Minas Gerais, 36036-900, Brazil.
Orlando V SousaDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Campus Universitário, São Pedro, Minas Gerais, 36036-900, Brazil. orlando.sousa@ufjf.edu.br.
Universidade Federal de Juiz de Fora · BR

Funding

CAPES AUX-PE-PNPD-2893/2011FAPEMIG CDS - APQ-01805-12
6 · The paper itself

Abstract

Palicourea rigida Kunth is traditionally used for the treatment of skin diseases, kidney pains and ovarian inflammation. Based on these traditional uses, this study evaluated the topical anti-inflammatory activity of the ethanol extract from P. rigida leaves (EEPR) and identified bioactive compounds. Ear edema was induced in Swiss mice by the topical application of Croton oil, arachidonic acid, phenol and capsaicin. Histopathological analysis and myeloperoxidase and N-acetyl-β-D-glucosaminidase activities were determined. EEPR was characterized by UHPLC-UV-MS HPLC and the isolated compound was identified through

Indexed as

Administration, TopicalAnimalsAnti-Inflammatory AgentsChromatography, High Pressure LiquidDisease Models, AnimalEdemaInflammationMaleMiceMolecular Docking SimulationPlant ExtractsPlant LeavesRubiaceaeAnti-Inflammatory AgentsPlant ExtractsEar edemaMolecular dockingMyeloperoxidaseN-Acetyl-β-D-glucosaminidasePalicourea rigidaQuercetin 3-O-β-D-glucoside

Identifiers

PMID29138954
OpenAlexW2770686369

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.