ReviewJournal of clinical immunology2018
Chronic Diarrhea in Common Variable Immunodeficiency: a Case Series and Review of the Literature.
Review in Journal of clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Evaluation of intestinal fungal and parasitic infection in iranian primary immunodeficiency patients.Molecular biology reports · 2026Article
- Gastrointestinal Tract Findings in Patients with Primary Immunodeficiency: A Single-Center 6-Year Experience.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025Article
- A Broad Spectrum of Liver Manifestations in Common Variable Immunodeficiency Syndrome-Two Case Reports and a Literature Overview.Diagnostics (Basel, Switzerland) · 2025Article
- Endoscopic and histopathological hints on infections in patients of common variable immunodeficiency disorder with gastrointestinal symptoms.BMC gastroenterology · 2023Article
- Dysbiosis and primary B-cell immunodeficiencies: current knowledge and future perspective.Immunologic research · 2023Review
- Chronic Diarrhea with Villous Blunting of the Small Intestine Under Capsule Endoscopy in Common Variable Immunodeficiency and X-Linked Agammaglobulinemia: A Case Series.Journal of asthma and allergy · 2023Article
- Liver disease accompanied by enteropathy in common variable immunodeficiency: Common pathophysiological mechanisms.Frontiers in immunology · 2022Article
- Gut Microbiome and Common Variable Immunodeficiency: Few Certainties and Many Outstanding Questions.Frontiers in immunology · 2021Review
- From infections to autoimmunity: Diagnostic challenges in common variable immunodeficiency.World journal of clinical cases · 2020Review
- Primary Humoral Immune Deficiencies: Overlooked Mimickers of Chronic Immune-Mediated Gastrointestinal Diseases in Adults.International journal of molecular sciences · 2020Review
- Heterogeneity of Liver Disease in Common Variable Immunodeficiency Disorders.Frontiers in immunology · 2020Review
- Primary immunodeficiency disease: a retrospective study of 112 Chinese children in a single tertiary care center.BMC pediatrics · 2019Article
- Gastrointestinal Disorders Associated with Primary Immunodeficiency Diseases.Clinical reviews in allergy & immunology · 2019Review
- Gastrointestinal Manifestations and Complications of Primary Immunodeficiency Disorders.Immunology and allergy clinics of North America · 2019Review
- Immunosuppressive therapy with rituximab in common variable immunodeficiency.Clinical and molecular allergy : CMA · 2019Review
- [Gastrointestinal tract diseases induced by medications].Der Pathologe · 2018Review
- Hypogammaglobulinemic sprue manifested as chronic intestinal failure: An uncommon but effective indication for home parenteral nutrition.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by reduced immunoglobulin serum levels and absent or impaired antibody production. Clinical manifestations, including infections, inflammatory and autoimmune diseases, and malignancies, also involve various segments of the gastrointestinal tract. Chronic diarrhea is one of the most common gastrointestinal symptoms and may cause a wide spectrum of potentially life-threatening conditions as malabsorption and protein-energy malnutrition. We describe three female CVID adult patients presenting with chronic diarrhea, weight loss, and protein-energy malnutrition due to different underlying conditions. Our review of the literature explores the various gastrointestinal involvements in CVID and points out several histopathological findings proper of the disease, thus highlighting the relevance of the endoscopic and histological assessment in CVID patients presenting with chronic diarrhea.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.