ArticleAdvances in orthopedics2017
Use of Common Inflammatory Markers in the Long-Term Screening of Total Hip Arthroprosthesis Infections: Our Experience.
Article in Advances in orthopedics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Inflammatory blood parameters as prognostic factors for implant-associated infection after primary total hip or knee arthroplasty: a systematic review.BMC musculoskeletal disorders · 2023Pooled it
- Development and Internal Evaluation of a Biomarker-Based Model for Preoperative Diagnosis of Infectious Nonunion.Orthopaedic surgery · 2026Article
- A three-biomarker panel for frailty prediction and risk stratification in institutionalized older adults: a multicenter validation study.European geriatric medicine · 2026Article
- Diagnostic Values of Serum Inflammatory Biomarkers after Hip and Knee Arthroplasty in Patients with Periprosthetic Joint Infection.Healthcare (Basel, Switzerland) · 2024Article
- Diagnostic Performance of a Molecular Assay in Synovial Fluid Targeting Dominant Prosthetic Joint Infection Pathogens.Microorganisms · 2024Article
- Hypoalbuminemia and Elevated CRP are Risk Factors for Deep Infections and Urinary Tract Infections After Lumbar Spine Surgery in a Large Retrospective Patient Population.Global spine journal · 2023Article
- Metallic Implants Used in Lumbar Interbody Fusion.Materials (Basel, Switzerland) · 2022Review
- The influence of different THA surgical approaches on Patient's early postoperative anxiety and depression.BMC musculoskeletal disorders · 2021Article
- Cemented hemiarthroplasty versus proximal femoral nail antirotation in the management of intertrochanteric femoral fractures in the elderly: a case control study.BMC musculoskeletal disorders · 2021Article
- Management of pertrochanteric fractures in patients over 90 years: In-hospital mortality rate, complications and associated risk factors.BMC musculoskeletal disorders · 2021Article
- Comparing the use of preformed vs hand-made antibiotic spacer cement in two stages revision of hip periprosthetic infection.Journal of clinical orthopaedics and trauma · 2020Article
- Effectiveness of circular hexapod external fixation with soft tissue reconstruction in treating severe knee dislocation due to burn scarring: a case report.BMC musculoskeletal disorders · 2020Article
- Effectiveness of circular external fixator in periprosthetic fractures around the knee.BMC musculoskeletal disorders · 2020Article
- The Comparative Analysis of Antegrade Versus Retrograde Approach for a Failed Porous Tantalum Rod Removal During Conversion to Total Hip Arthroplasty.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Treatment of a Recalcitrant Non-union of the Clavicle.Strategies in trauma and limb reconstructionArticle
- The challenge of nonunion after osteosynthesis of the clavicle: is it a biomechanical or infection problem?Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal DiseasesArticle
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthopedic implants have become essential components of modern medicine. The risk of infection of total hip arthroplasty (THA) is 1.5%-2%. Are the C-reactive protein (CRP), the erythrocyte sedimentation rate (ESR), and procalcitonin (PCT) good markers for THA infection screenings? From February 2009 to December 2012 at our Department of Orthopedics and Traumatology, 1248 patients were treated with THA. No prosthesis was cemented. All patients received antibiotic prophylaxis. All patients were discharged approximately 7.4 days after surgery with this clinical and radiographic follow-up program at 15 days and 1, 3, 6, 12, 24, and 36 months after surgery. Blood samples to determine ESR, CRP, and PCT values were taken at 1 hour before surgery and 15 days and 1, 3, 6, 12, 24, and 36 months after surgery. During follow-ups there were 22 cases of THA infections; according the Widmer classification, infections are hematogenous ones in 16 cases, late chronic ones in 5 cases, and early postoperative ones in 1 case. In all cases the three markers were considered positive; in 6 cases there were no radiological signs of septic loosening. ESR, CRP, and PCT proved to have a greater diagnostic accuracy than X-rays in predicting late chronic and early postoperative infections. These markers are valuable support for the surgeon in monitoring the prosthetic implant lifespan.
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Registered trials
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