Evidence map›Paper›PMID 29138641›Full record

ArticleJournal of tropical medicine2017

Naturally Acquired Antibody Responses to a Synthetic Malaria Antigen AS202.11.

Rebeka Nazareth, Pius Horumpende, Tolbert Sonda, Arnold Ndaro, Edson Mollel, Eliakim Paul, Emmanuel Athanase, Jaffu Chilongola

Abstract read
In one paragraph

Article in Journal of tropical medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rebeka NazarethKilimanjaro Christian Medical University College, P.O. Box 2240, Moshi, Tanzania.
Pius HorumpendeKilimanjaro Christian Medical University College, P.O. Box 2240, Moshi, Tanzania.
Tolbert SondaKilimanjaro Christian Medical University College, P.O. Box 2240, Moshi, Tanzania.
Arnold NdaroKilimanjaro Clinical Research Institute, P.O. Box 2236, Moshi, Tanzania.
Edson MollelKibong'oto Infectious Diseases Hospital, P.O. Box 12, Sanya Juu, Siha, Tanzania.ORCID 0000-0003-1583-6321
Eliakim PaulKilimanjaro Christian Medical University College, P.O. Box 2240, Moshi, Tanzania.
Emmanuel AthanaseNewala Town Council Hospital, P.O. Box 39, Newala, Tanzania.
Jaffu ChilongolaKilimanjaro Christian Medical University College, P.O. Box 2240, Moshi, Tanzania.ORCID 0000-0003-2997-6747

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA major challenge to malaria vaccine development is identification of protective epitopes and respective protective immune responses.

objectiveTo characterize naturally acquired Immunoglobulin G (IgG) responses to the synthetic peptide AS202.11, a malaria vaccine candidate. METHODOLOGY: This community based cross-sectional study enrolled 320 participants aged 1 year and above. Demographic information was recorded through interviews. Detection of

resultsThe overall AS202.11 IgG seropositivity was 78.8% (73.9-82.9). Seropositivity by age categories was ≤12 years [74.3% (67.4-80.2)], 13-40 years [85.3% (76.5-91.1)], and >40 years [82.6% (68.7-91.1)]. Compared to the ≤ 12-year-old group, aORs for the other groups were 2.22 (1.14-4.32),

conclusionWe report a high degree of recognition of AS202.11 by IgG elicited by field

Identifiers

PMID29138641
PMCPMC5613363

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