Evidence map›Paper›PMID 29138566›Full record

ArticleInternational journal of nanomedicine2017

Studies on the use of recombinant spider silk protein/polyvinyl alcohol electrospinning membrane as wound dressing.

Liang Zhao, Denglong Chen, Qinghua Yao, Min Li

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Nanostructured Protein Surfaces Inspired by Spider Silk.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Silkworm and spider silk electrospinning: a review.Environmental chemistry letters · 2021
    Review
  8. Review
  9. Evaluation of remodeling and regeneration of electrospun PCL/fibrin vascular grafts in vivo.Materials science & engineering. C, Materials for biological applications · 2021
    Article
  10. Silk fibroin and silk-based biomaterial derivatives for ideal wound dressings.International journal of biological macromolecules · 2020
    Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Liang Zhao *College of Life Sciences and Technology Xinxiang Medical University, Henan.
Denglong Chen *College of Life Sciences, Fujian Normal University, Fuzhou.
Qinghua YaoCollege of Life Sciences, Fujian Normal University, Fuzhou.
Min LiCollege of Life Sciences, Fujian Normal University, Fuzhou.
Fujian Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of wound membranes of polyvinyl alcohol and recombinant spider silk protein (pNSR16) was prepared by electrospinning. The membrane was analyzed by scanning electron microscopy, atomic force microscopy, and Fourier transform infrared spectroscopy. The result showed that the three factors that affected average fiber diameter from high to low were, voltage, flow speed, and solidification distance; and the three factors that affected fiber uniformity from high to low were, flow speed, solidification distance, and voltage. The fibers adhered together after being dealt with alcohol. pNSR16 transformed from random coil into β-sheet after being immersed in alcohol. Additionally, the porosity of the electrospun membrane was 84.85%, which was higher than that of cast membrane prepared with the same composition. Experiments of applying electrospun membranes as wound dressing for Sprague Dawley rat wound healing showed that it could promote wound healing and basic fibroblast growth factor expression.

Indexed as

Biological DressingsWound HealingAnimalsBiocompatible MaterialsBurnsFibroinsOligopeptidesPolyvinyl AlcoholPorosityRats, Sprague-DawleyRecombinant ProteinsSilkSkinSpidersarginyl-glycyl-aspartic acidBiocompatible MaterialsFibroinsOligopeptidesPolyvinyl AlcoholRecombinant ProteinsSilkspidroin 2characterizationelectrospinningpolyvinyl alcoholrecombinant spider silk proteinwound dressing

Identifiers

PMID29138566
PMCPMC5679674
OpenAlexW2766057082

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.