Evidence map›Paper›PMID 29138564›Full record

ArticleInternational journal of nanomedicine2017

Zinc oxide nanoparticles induce toxic responses in human neuroblastoma SHSY5Y cells in a size-dependent manner.

Jia Liu, Yiyuan Kang, Suhan Yin, Bin Song, Limin Wei, Liangjiao Chen, Longquan Shao

Erratum issuedAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jia LiuDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou.
Yiyuan KangDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou.
Suhan YinDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou.
Bin SongDepartment of Stomatology, Guizhou Provincial People's Hospital, Guiyang.
Limin WeiDepartment of Pediatric Dentistry, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou.
Liangjiao ChenKey Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.
Longquan ShaoDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the widespread applications of zinc oxide nanoparticles (ZnO NPs), the potential exposure of workers, consumers, and scientists to these particles has increased. This potential for exposure has attracted extensive attention in the science community. Many studies have examined the toxicological profile of ZnO NPs in the immune system, digestive system, however, information regarding the toxicity of ZnO NPs in the nervous system is scarce. In this study, we detected the cytotoxicity of two types of ZnO NPs of various sizes - ZnO

Indexed as

ApoptosisCell Line, TumorCell SurvivalHumansNanoparticlesNeuroblastomaOxidative StressParticle SizeReactive Oxygen SpeciesZinc OxideReactive Oxygen SpeciesZinc Oxideapoptosiscell cytoskeletonnanoparticlesreactive oxygen speciesSHSY5Y cellszinc oxide

Identifiers

PMID29138564
PMCPMC5677299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.