Evidence map›Paper›PMID 29138445›Full record

ArticleScientific reports2017

Inhibition activity of a traditional Chinese herbal formula Huang-Lian-Jie-Du-Tang and its major components found in its plasma profile on neuraminidase-1.

Xuelin Zhou, Haotian Li, Zhilong Shi, Sijia Gao, Shizhang Wei, Kun Li, Jiabo Wang, Jianyu Li, Ruilin Wang, Man Gong and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Mechanism ofAnnals of translational medicine · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Xuelin ZhouDepartment of Pharmacy, 302 Military Hospital of China, Beijing, People's Republic of China.
Haotian LiDepartment of Pharmacy, 302 Military Hospital of China, Beijing, People's Republic of China.
Zhilong ShiChina Military Institute of Chinese Medicine, 302 Military Hospital of China, Beijing, People's Republic of China.
Sijia GaoDepartment of Pharmacy, 302 Military Hospital of China, Beijing, People's Republic of China.
Shizhang WeiDepartment of Pharmacy, 302 Military Hospital of China, Beijing, People's Republic of China.
Kun LiDepartment of Pharmacy, 302 Military Hospital of China, Beijing, People's Republic of China.
Jiabo WangChina Military Institute of Chinese Medicine, 302 Military Hospital of China, Beijing, People's Republic of China.
Jianyu LiIntegrative Medical Center, 302 Military Hospital of China, Beijing, People's Republic of China.
Ruilin WangIntegrative Medical Center, 302 Military Hospital of China, Beijing, People's Republic of China.
Man GongIntegrative Medical Center, 302 Military Hospital of China, Beijing, People's Republic of China.
Yanling ZhaoDepartment of Pharmacy, 302 Military Hospital of China, Beijing, People's Republic of China. zhaoyl2855@126.com.
Xiaohe XiaoChina Military Institute of Chinese Medicine, 302 Military Hospital of China, Beijing, People's Republic of China.
302 Military Hospital of China · CNChinese People's Liberation Army · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huang-Lian-Jie-Du-Tang (HLJDT), a traditional formula with four TCM herbs, has been used for hundred years for different diseases. The current study aimed to assess the inhibitory activity of HLJDT against H1N1 neuraminidase (NA-1), and identify potent NA-1 inhibitors from its plasma profile. The in vitro NA-1 study has shown that the water extract of HLJDT potently inhibited NA-1 (IC

Indexed as

AnimalsBerberineBerberine AlkaloidsCoptis chinensisCrystallographyDrugs, Chinese HerbalEnzyme InhibitorsFlavanonesGardeniaHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanMedicine, Chinese TraditionalMolecular Docking SimulationNeuraminidaseRatsbaicaleinBerberineBerberine AlkaloidsCoptidis rhizoma extractDrugs, Chinese HerbalEnzyme InhibitorsFlavanoneshuang-lien-chieh-tu-tangjatrorrhizineNeuraminidasepalmatinewogonin

Identifiers

PMID29138445
PMCPMC5686190
OpenAlexW2767436962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.