ArticleNPJ primary care respiratory medicine2017
Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study.
Article in NPJ primary care respiratory medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02307799 (A RESearch on the PrEvalence and the Diagnosis of COPD and Its Tobacco-related Etiology), which is not on this map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A RESearch on the PrEvalence and the Diagnosis of COPD and Its Tobacco-related Etiology (RESPECT)
Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Active Case Finding of Chronic Obstructive Pulmonary Disease in Romanian Primary Care.Medicina (Kaunas, Lithuania) · 2026Article
- Plasma metabolomic signatures enable the diagnosis and prognosis of chronic obstructive pulmonary disease.Nature communications · 2026Article
- A baseline study of interpretable machine learning using GC-MS breath VOCs for classifying asthma, bronchiectasis, and COPD.Scientific reports · 2025Article
- Fibrotic and emphysematous murine lung mechanics under negative-pressure ventilation.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Chronic obstructive Pulmonary Disease (COPD) in non-smoking Sri Lankan adults; a cross-sectional study.BMC research notes · 2025Article
- Article
- Evaluation of Salivary Biomarkers and Spirometry for Diagnosing COPD in Non-Smokers and Smokers of Polish Origin.Biomedicines · 2024Article
- Screening and staging of chronic obstructive pulmonary disease with deep learning based on chest X-ray images and clinical parameters.BMC pulmonary medicine · 2024Article
- Quantitative analyzes of the variability in airways via four-dimensional dynamic ventilation CT in patients with chronic obstructive pulmonary disease: correlation with spirometry data and severity of airflow limitation.Journal of thoracic disease · 2023Article
- Assessing four-dimensional CT stress maps derived from patient-specific biomechanical models of the lung with pulmonary function test data in lung cancer patients.The British journal of radiology · 2023Article
- Investigation of time profile of FEVScientific reports · 2023Article
- Diagnostic efficacy of visual subtypes and low attenuation area based on HRCT in the diagnosis of COPD.BMC pulmonary medicine · 2022Article
- Lung proteomic biomarkers associated with chronic obstructive pulmonary disease.American journal of physiology. Lung cellular and molecular physiology · 2021Article
- Inflammatory parameters and pulmonary biomarkers in smokers with and without chronic obstructive pulmonary disease (COPD).Journal of thoracic disease · 2021Article
- Computed tomography-based visual assessment of chronic obstructive pulmonary disease: comparison with pulmonary function test and quantitative computed tomography.Journal of thoracic disease · 2021Article
- Artificial Intelligence and Machine Learning in Chronic Airway Diseases: Focus on Asthma and Chronic Obstructive Pulmonary Disease.International journal of medical sciences · 2021Review
- Recent applications and strategies in nanotechnology for lung diseases.Nano research · 2021Review
- Article
- Prevalence of Chronic Obstructive Pulmonary Disease and its Associated Factors in Nepal: Findings from a Community-based Household Survey.International journal of chronic obstructive pulmonary disease · 2020Article
- Respiratory Sound Based Classification of Chronic Obstructive Pulmonary Disease: a Risk Stratification Approach in Machine Learning Paradigm.Journal of medical systems · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A hallmark of the diagnosis of chronic obstructive pulmonary disease (COPD) is the measurement of post-bronchodilator (post-BD) airflow obstruction (AO) by spirometry, but spirometry is not enough for the provision of a clinical diagnosis. In the majority of previous epidemiological studies, COPD diagnosis has been based on spirometry and a few clinical characteristics. The aim of our study was to identify outcomes in patients newly diagnosed with airflow obstruction (AO) based on a diagnostic work-up conducted as part of a population-based cross-sectional study in North-Western Russia. Spirometry was performed before (pre-BD) and after BD administration, and AO was defined using the FEV1/FVC <0.70 and FEV1/FVC <lower limit of normal cut-off values. Relevant symptoms were recorded. Participants with AO identified at baseline were then examined by a pulmonologist, including a clinical examination and second spirometry with BD test. Of the 102 participants with post-BD AO in the initial assessment, only 60.8% still had AO identified at the second examination; among these patients, the following final diagnoses were reported: COPD (n = 41), asthma (n = 5), asthma-COPD overlap syndrome (ACOS) (n = 4) and likely ACOS (n = 5). Of the 65 participants with pre-BD AO, 23.1% had post-BD AO at the second assessment, and these patients had been diagnosed with COPD (n = 12), asthma (n = 1), ACOS (n = 1), likely ACOS (n = 1). Serial spirometric assessments complemented by a comprehensive clinical evaluation are recommended in new epidemiological studies.
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