Evidence map›Paper›PMID 29138251›Full record

ArticleThe Journal of cell biology2018

Mitochondrial inner-membrane protease Yme1 degrades outer-membrane proteins Tom22 and Om45.

Xi Wu, Lanlan Li, Hui Jiang

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 41 citations in OpenAlex.

  1. Proteolytic control of mitochondrial protein translocases.Protein science : a publication of the Protein Society · 2026
    Review
  2. In and out of the mitochondrial intermembrane space.Protein science : a publication of the Protein Society · 2026
    Review
  3. Article
  4. Ecm19 coordinates mitochondrial fission and cellular redox homeostasis.Redox report : communications in free radical research · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Review
  12. Review
  13. Review
  14. Quality control of the mitochondrial proteome.Nature reviews. Molecular cell biology · 2021
    Review
  15. Article
  16. Protein Quality Control at the Mitochondrial Surface.Frontiers in cell and developmental biology · 2021
    Review
  17. CHCHD10-regulated OPA1-mitofilin complex mediates TDP-43-induced mitochondrial phenotypes associated with frontotemporal dementia.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  18. Article
  19. Output Regulation and Function Optimization of Mitochondria in Eukaryotes.Frontiers in cell and developmental biology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Xi WuSchool of Life Sciences, Peking University, Beijing, China wuxi@nibs.ac.cn.ORCID 0000-0002-9327-139X
Lanlan LiCollege of Life Sciences, Beijing Normal University, Beijing, China.
Hui JiangNational Institute of Biological Sciences, Beijing, China jianghui@nibs.ac.cn.ORCID 0000-0002-0277-9711
Beijing Normal University · CNNational Institute of Biological Sciences, Beijing · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are double-membraned organelles playing essential metabolic and signaling functions. The mitochondrial proteome is under surveillance by two proteolysis systems: the ubiquitin-proteasome system degrades mitochondrial outer-membrane (MOM) proteins, and the AAA proteases maintain the proteostasis of intramitochondrial compartments. We previously identified a Doa1-Cdc48

Indexed as

ATP-Dependent ProteasesCarrier ProteinsMembrane ProteinsMitochondriaMitochondrial MembranesMitochondrial Membrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsMitochondrial ProteinsProteolysisProteostasisSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsATP-Dependent ProteasesCarrier ProteinsMembrane ProteinsMgr1 protein, S cerevisiaeMgr3 protein, S cerevisiaeMitochondrial Membrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsMitochondrial ProteinsOm45 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTOM22 protein, S cerevisiaeYME1 protein, S cerevisiae

Identifiers

PMID29138251
PMCPMC5748973
OpenAlexW2770699742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.