Evidence map›Paper›PMID 29138237›Full record

ArticleG3 (Bethesda, Md.)2018

Natural Variation in

Amy Sirr, Adrian C Scott, Gareth A Cromie, Catherine L Ludlow, Vida Ahyong, Trey S Morgan, Teresa Gilbert, Aimée M Dudley

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Natural variation of chronological aging in theNPJ aging and mechanisms of disease · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Amy SirrPacific Northwest Research Institute, Seattle, Washington 98122.ORCID 0000-0002-5186-9692
Adrian C ScottPacific Northwest Research Institute, Seattle, Washington 98122.ORCID 0000-0003-4511-0898
Gareth A CromiePacific Northwest Research Institute, Seattle, Washington 98122.ORCID 0000-0001-5265-1970
Catherine L LudlowPacific Northwest Research Institute, Seattle, Washington 98122.ORCID 0000-0001-9682-7851
Vida AhyongDepartment of Molecular and Cellular Biology, University of California, Berkeley, California 94720.ORCID 0000-0002-8632-9629
Trey S MorganPacific Northwest Research Institute, Seattle, Washington 98122.ORCID 0000-0002-9299-8562
Teresa Gilbert
Aimée M DudleyPacific Northwest Research Institute, Seattle, Washington 98122 aimee.dudley@gmail.com.ORCID 0000-0003-3644-0625
Pacific Northwest Diabetes Research Institute · USUniversity of California, Berkeley · US

Funding

Computation and functional significance of multi-phenotype genetic interaction maR01GM089978 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI DUDLEY, AIMEE M, SEGRE, DANIEL · 2010 to 2014
$2.3M
NIGMS NIH HHS R01 GM089978
6 · The paper itself

Abstract

Despite their ubiquitous use in laboratory strains, naturally occurring loss-of-function mutations in genes encoding core metabolic enzymes are relatively rare in wild isolates of

Indexed as

Gene Expression Regulation, FungalGenome, FungalPolymorphism, GeneticAlcoholic BeveragesCaffeineCopperCulture MediaEthanolFermentationHumansMolecular Sequence AnnotationPromoter Regions, GeneticQuantitative Trait LociRepressor ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCaffeineCopperCulture MediaEthanolMIG1 protein, S cerevisiaeNRG1 protein, S cerevisiaephosphoserine aminotransferaseRepressor ProteinsSaccharomyces cerevisiae ProteinsSaltsSirolimusSodium-Potassium-Exchanging ATPaseTransaminasesnatural variationQTL mappingsalt stressserine metabolismyeast

Identifiers

PMID29138237
PMCPMC5765352
OpenAlexW2768414954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.