ArticleBMJ open2017
MONITOR-IC study, a mixed methods prospective multicentre controlled cohort study assessing 5-year outcomes of ICU survivors and related healthcare costs: a study protocol.
Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03246334 (MONITOR-IC), which is not on this map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
MONITOR-IC: a Mixed Methods Multicenter Prospective Open Cohort Study Determining and Improving Long-term Outcomes of ICU Survivors
Who cites it
23 citing papers in PubMed.
- Discussing expected long-term quality of life in the ICU: effect on experiences and outcomes of patients, family, and clinicians-a randomized clinical trial.Intensive care medicine · 2025Trial
- Effect of an intensive care unit virtual reality intervention on relatives´ mental health distress: a multicenter, randomized controlled trial.Critical care (London, England) · 2025Trial
- Data Resource Profile Update: The Dutch National Intensive Care Evaluation (NICE) registry.International journal of epidemiology · 2026Article
- Identifying distinct clusters of ICU survivors by integrating demographic, pre-admission quality of life, and clinical data: a large prospective cohort study.Intensive care medicine · 2025Article
- Getting valuable and valid insight in life after ICU: evaluating the representativeness of a large cohort of ICU survivors.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2025Article
- Associations Between Physical, Cognitive, and Mental Health Domains of Post-Intensive Care Syndrome and Quality of Life: A Longitudinal Multicenter Cohort Study.Critical care medicine · 2025Article
- Changes in quality of life 1 year after intensive care: a multicenter prospective cohort of ICU survivors.Critical care (London, England) · 2024Article
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- Article
- Two-year physical, mental and cognitive outcomes among intensive care unit survivors treated for COVID-19.Intensive care medicine · 2023Article
- Optimizing an existing prediction model for quality of life one-year post-intensive care unit: An exploratory analysis.Acta anaesthesiologica Scandinavica · 2022Article
- Long-Term Impairments Are Most Pronounced in Critically Ill Patients with COVID-19 with Severe Obesity.American journal of respiratory and critical care medicine · 2022Article
- Article
- A Quality Improvement Project to Support Post-Intensive Care Unit Patients with COVID-19: Structured Telephone Support.International journal of environmental research and public health · 2022Article
- Baseline Anxiety and Depression and Risk for ICU Delirium: A Prospective Cohort Study.Critical care explorations · 2022Article
- Mature neutrophils and a NF-κB-to-IFN transition determine the unifying disease recovery dynamics in COVID-19.Cell reports. Medicine · 2022Article
- Mental health symptoms in family members of COVID-19 ICU survivors 3 and 12 months after ICU admission: a multicentre prospective cohort study.Intensive care medicine · 2022Article
- Exploring Ketamine Analgosedation Use and Its Effect on Incident Delirium in Critically Ill Adults.Critical care explorations · 2021Article
- Social Determinants of Health and Delirium Occurrence and Duration in Critically Ill Adults.Critical care explorations · 2021Article
- Shared decision-making in the ICU from the perspective of physicians, nurses and patients: a qualitative interview study.BMJ open · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDue to advances in critical care medicine, more patients survive their critical illness. However, intensive care unit (ICU) survivors often experience long-term physical, cognitive and mental problems, summarised as post-intensive care syndrome (PICS), impacting their health-related quality of life (HRQoL). In what frequency PICS occurs, and to what extent this influences ICU survivors' HRQoL, is mostly unknown. The aims of this study are therefore to study the: (1) 5-year patient outcomes, (2) predictors for PICS, (3) ratio between HRQoL of ICU survivors and healthcare-related costs, and (4) care and support needs.
methodsThe MONITOR-IC study is a multicentre prospective controlled cohort study, carried out in ICUs in four Dutch hospitals. Patients will be included between July 2016 and July 2021 and followed for 5 years. We estimated to include 12000 ICU patients. Outcomes are the HRQoL, physical, cognitive and mental symptoms, ICU survivors' care and support needs, healthcare use and related costs. A control cohort of otherwise seriously ill patients will be assembled to compare long-term patient-reported outcomes. We will use a mixed methods design, including questionnaires, medical data from patient records, cost data from health insurance companies and interviews with patients and family members. ETHICS AND DISSEMINATION: Insights from this study will be used to inform ICU patients and their family members about long-term consequences of ICU care, and to develop prediction and screening instruments to detect patients at risk for PICS. Subsequently, tailored interventions can be developed and implemented to prevent and mitigate long-term consequences. Additionally, insights into the ratio between HRQoL of ICU patients and related healthcare costs during 5 years after ICU admission can be used to discuss the added value of ICU care from a community perspective. The study has been approved by the research ethics committee of the Radboud University Medical Center (2016-2724). CLINICAL
trial registrationNCT03246334.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.