Trial reportJournal of orthopaedic surgery and research2017
Influence of tourniquet use in primary total knee arthroplasty with drainage: a prospective randomised controlled trial.
Trial report in Journal of orthopaedic surgery and research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Total knee arthroplasty with or without a tourniquet: a meta-analysis of randomized controlled trials.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Pooled it
- Impact of tourniquet during total knee arthroplasty when tranexamic acid was used: a meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2022Pooled it
- Association of Use of Tourniquets During Total Knee Arthroplasty in the Elderly Patients With Post-operative Pain and Return to Function.Frontiers in public health · 2022Pooled it
- A comparison of thrombosis in total knee arthroplasty with and without a tourniquet: a meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2021Pooled it
- Impact of tourniquet during knee arthroplasty: a bayesian network meta-analysis of peri-operative outcomes.Archives of orthopaedic and trauma surgery · 2021Pooled it
- Time to reconsider the routine use of tourniquets in total knee arthroplasty surgery.The bone & joint journal · 2021Pooled it
- Tourniquet use for knee replacement surgery.The Cochrane database of systematic reviews · 2020Pooled it
- More pain and slower functional recovery when a tourniquet is used during total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Pooled it
- An updated meta-analysis evaluating limb management after total knee arthroplasty-what is the optimal method?Journal of orthopaedic surgery and research · 2019Pooled it
- Tourniquet use in lower limb fracture surgery: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2019Pooled it
- Liposomal bupivacaine in peri-articular injection reduces opioid consumption and improves early prognosis of total knee arthroplasty: a randomized controlled trial.BMC musculoskeletal disorders · 2026Trial
- Effects of special waterproof layer under tourniquet cuff on the incidence of burns and pain intensity and satisfaction of operating room staff in knee arthroscopic surgeries: a randomized clinical trial.Journal of orthopaedic surgery and research · 2025Trial
- Tourniquets can further reduce perioperative blood loss in patients on dexamethasone and tranexamic acid during cemented total knee arthritis: a single-center, double-blind, randomized controlled trial.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2023Trial
- Risk factor of postoperative incision infection after plate internal fixation of calcaneal fractures: a retrospective study.BMC musculoskeletal disorders · 2022Trial
- Effect of tourniquet use on blood loss, pain, functional recovery, and complications in robot-assisted total knee arthroplasty: a prospective, double-blinded, randomized controlled trial.Journal of orthopaedic surgery and research · 2022Trial
- Optimal Handling of the Patella in Tourniquet-Free Total Knee Arthroplasty: Eversion or Lateral Retraction?Orthopaedic surgery · 2020Trial
- A small difference in recovery between total knee arthroplasty with and without tourniquet use the first 3 months after surgery: a randomized controlled study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Trial
- Effect of controlled hypotension combined with low-pressure tourniquet on hemoglobin reduction after total knee arthroplasty.BMC surgery · 2026Article
- Posterior cruciate ligament reconstruction without tourniquet use reduces joint swelling without compromising surgical outcomes: a retrospective study.Scientific reports · 2025Article
- Association of tourniquet use on short-term implant survival after primary total knee arthroplasty: a study of 24,249 knees from the Norwegian Arthroplasty Register.Acta orthopaedica · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundWe aimed to compare the effect of tourniquet use or lack of it on recovery following uncomplicated primary total knee arthroplasty (TKA).
methodsIn a prospective randomised double-blinded study, 150 patients undergoing primary TKA were assigned to either a tourniquet or non-tourniquet group. At the early phase, 3 and 6 months after surgery, an independent observer assessed the primary outcome measure (i.e. total blood loss) and secondary outcome measures (i.e. wound complications, visual analogue scale pain score and knee range of motion).
resultsThe tourniquet group exhibited reduced intraoperative blood loss (215.7 ± 113.7 ml vs. 138.6 ± 93.9 ml, P < 0.001) and shorter operating time (77.2 ± 14.5 min vs. 82.0 ± 12.7 min, P = 0.038). However, the non-tourniquet group showed less postoperative blood loss (180.2 ± 117.0 ml vs. 253.7 ± 144.2 ml, P = 0.001) and drainage volume (89.2 ± 66.3 ml vs. 164.5 ± 97.8 ml, P = 0.004), less thigh pain (all P < 0.001) in the initial 3 weeks, better knee range of motion (ROM) in the initial 3 days (day 1 81.6 ± 17.1 vs. 75.95 ± 14.55, P = 0.036; day 3 99.8 ± 13.7 vs. 93.95 ± 11.15, P = 0.005) and fewer wound tension vesicles (10.3 vs. 29.2%, P = 0.005). Earlier straight-leg raising (4.6 ± 3.8 h vs. 6.4 ± 4.3 h, P = 0.01) and shorter length of stay (6.3 ± 1.7 days vs. 7.1 ± 1.9 days, P = 0.001) were found in the non-tourniquet group. Similar total blood loss and blood transfusion rate were observed for both groups. All other parameters revealed no significant differences.
conclusionsOur study suggests that a non-tourniquet TKA would lead to early rehabilitation without increasing side effects.
trial registrationChinese Clinical Trials Registry, ChiCTR-IOR-16007851 , 1/29/2016.
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