Evidence map›Paper›PMID 29137635›Full record

ArticleLipids in health and disease2017

The association between serum 25-hydroxyvitamin D3 concentration and serum lipids in the rural population of China.

Huina Ge, Hualei Sun, Teng Wang, Xinxin Liu, Xing Li, Fei Yu, Han Han, Jun Wang, Wenjie Li

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. The Relationship of 25(OH)DMedicina (Kaunas, Lithuania) · 2022
    Article
  6. Article
  7. Article
  8. Association of serum 25-Hydroxy Vitamin D level with lipid, lipoprotein, and apolipoprotein level.Journal of community hospital internal medicine perspectives · 2021
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Huina GeDepartment of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Henan, 450001, China.
Hualei SunDepartment of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Henan, 450001, China.
Teng WangDepartment of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Henan, 450001, China.
Xinxin LiuDepartment of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Henan, 450001, China.
Xing LiDepartment of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Henan, 450001, China.
Fei YuDepartment of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Henan, 450001, China.
Han HanDepartment of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Henan, 450001, China.
Jun WangDepartment of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Henan, 450001, China.
Wenjie LiDepartment of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Henan, 450001, China. lwj@zzu.edu.cn.
Zhengzhou University · CN

Funding

Dietary Nutrition Research and Education Foundation of Danone DIC2013-06National Nature Science Foundation of China 8157315, U1204823, and 81573243Science and Technology Foundation for Innovation Talent of Henan Province 154200510010
6 · The paper itself

Abstract

backgroundVitamin D deficiency is implicated in some diseases, including cardiovascular. Few studies have assessed the correlation between 25-hydroxyvitamin D3 [25(OH) D3] and serum lipids. In this study, we explored the correlation between serum 25(OH) D3 concentrations and serum lipids with a typical sample of the rural population in China.

methodsFace-to-face research was used to gather some basic information. Fasting serum concentrations of 25-(OH) D3, total cholesterol (TC), triglyceride (TG), HDL cholesterol (HDL-C) and, LDL cholesterol (LDL-C) tested in the laboratory.

resultsThe mean of serum 25(OH) D3 level was 28.71 ± 29.29 ng/mL. The results showed that the dyslipidemia was strongly associated with gender (P = 0.031), drinking (P = 0.043), high-fat diet intake (P = 0.017), HDL-C (P<0), TG (P<0), body mass index (BMI) (P<0) and serum 25(OH)D3 levels (P = 0.002). There was a positive correlation between serum 25(OH)D3 and HDL-C (P<0) in all groups. The relationship between 25(OH) D3 and LDL-C (P = 0.024) was discovered only in normal lipid group. The multivariable adjusted odds ratio (95%CI) of hypoalphalipoproteinemia/HDL and dyslipidemia by comparing the sufficiency vs. the deficiency serum 25-(OH) D3 level were 0.31 (0.192, 0.499) (P = 0.001) and 0.52 (0.36, 0.73) (P = 0.005), respectively.

conclusionsSerum 25(OH) D3 concentrations were associated with the serum lipids level and the association was different in normal serum lipid group and dyslipidemia group. With the increase of serum 25(OH) D3 levels, the incidence of dyslipidemia decreased.

Indexed as

Rural PopulationAgedCalcifediolChinaCholesterol, HDLCholesterol, LDLCross-Sectional StudiesDyslipidemiasFemaleHumansLipidsMaleMiddle AgedTriglyceridesCalcifediolCholesterol, HDLCholesterol, LDLLipidsTriglycerides25(oh)D3DyslipidemiaSerum lipid

Identifiers

PMID29137635
PMCPMC5686911
OpenAlexW2770548922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.