SynthesisBMC complementary and alternative medicine2017
Safety classification of herbal medicines used among pregnant women in Asian countries: a systematic review.
Synthesis in BMC complementary and alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Patient-physician communication on herbal medicine use during pregnancy: a systematic review and meta-analysis.BMJ global health · 2024Pooled it
- Safety classification of herbal medicine use among hypertensive patients: a systematic review and meta-analysis.Frontiers in pharmacology · 2024Pooled it
- Prevalence, motivation, and associated factors of medicinal herbs consumption in pregnant women from Eastern Mediterranean Regional Office: a systematic review.Pharmaceutical biology · 2023Pooled it
- Orally consumed ginger and human health: an umbrella review.The American journal of clinical nutrition · 2022Pooled it
- Trial
- Perinatal Outcomes After the Use of Kampo Medicines Containing Ephedra During Pregnancy.Pharmacoepidemiology and drug safety · 2025Article
- An ethnopharmacological survey of herbal medicines use among pregnant and postpartum women in Souss Massa (Morocco).Frontiers in pharmacology · 2025Article
- Medication use before and during pregnancy in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study.European journal of clinical pharmacology · 2024Article
- Risk of Major Congenital Malformations Associated with the Use of Japanese Traditional (Kampo) Medicine Containing Ephedra During the First Trimester of Pregnancy.Drugs - real world outcomes · 2024Article
- Article
- Integrated traditional herbal medicine in the treatment of gastrointestinal disorder: the pattern of use and the knowledge of safety among the Eastern Region Saudi population.BMC complementary medicine and therapies · 2023Article
- Prevalence, knowledge, and attitudes toward herbal medicines among pregnant women attending antenatal clinic in Prince Mansour Military Hospital in Taif.Journal of family medicine and primary care · 2023Article
- Phytopharmaceutical practices of traditional health practitioners in Burkina Faso: a cross-sectional study.BMC complementary medicine and therapies · 2023Article
- Assessing the safety and use of medicinal herbs during pregnancy: a cross-sectional study in São Paulo, Brazil.Frontiers in pharmacology · 2023Article
- The Hematopoietic Effect of Ninjinyoeito (TJ-108), a Traditional Japanese Herbal Medicine, in Pregnant Women Preparing for Autologous Blood Storage.Medicina (Kaunas, Lithuania) · 2022Article
- Herbal Medicines-Are They Effective and Safe during Pregnancy?Pharmaceutics · 2022Review
- Irrational Use of Selected Herbal Medicines During Pregnancy: A Pharmacoepidemiological Evidence From Yemen.Frontiers in pharmacology · 2022Article
- Article
- Use of Herbal Medicines Among Breastfeeding Mothers in Tanzania: A Cross-Sectional Study.Frontiers in pharmacology · 2022Article
- Exploring the Use of Herbal Treatments During Pregnancy Among Saudi Women: An application of the knowledge-attitude-practice model.Sultan Qaboos University medical journal · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh prevalence of herbal medicines used in pregnancy and the lack of information on their safety is a public concern. Despite this, no significant research has been done regarding potential adverse effects of using herbal medicines during pregnancy, especially among developing Asian countries.
methodsCross-sectional studies were searched up to year 2016 on PubMed/Medline and EMBASE, the data were extracted and quality of studies was assessed using the quality appraisal tool. The findings are reported in accordance to the PRISMA checklist (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). Classification on safety of identified herbal medicines was done based on current scientific literature.
resultsThis study included eight cross-sectional studies (2729 participants) from seven different Asian countries, of which 1283 (47.01%) women used one or more herbal medicines during pregnancy. Peppermint (22.8%), aniseed (14.7%), olibanum (12.9%), flixweed seed (12.2%) and ginger (11.5%) were the most frequently used herbal medicines. Out of the 33 identified herbal medicines, 13 were classified as safe to use, five as use with caution, eight were potentially harmful to use in pregnancy and information on seven herbal medicines was not available in the current literature.
conclusionsSeveral herbal medicines identified in this review were classified to be potentially harmful or the information regarding safety in pregnancy was missing. It is recommended that contraindicated herbal medicines should be avoided and other herbals should be taken under supervision of a qualified health care practitioner. The classification regarding safety of herbal medicines in pregnancy can be utilized to create awareness on prevention of adverse effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.