Evidence map›Paper›PMID 29137439›Full record

ArticleOncotarget2017

Association between alcohol consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies.

Zheng He, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yong-Xi Song, Zhong-Ran Ni, Hao Xu, Song-Cheng Yin, Xing-Yu Liu and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Zheng HeDepartment of Radiation Oncology, First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Ting-Ting ZhaoDepartment of Breast Surgery, First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Hui-Mian XuDepartment of Surgical Oncology, First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Zhen-Ning WangDepartment of Surgical Oncology, First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Ying-Ying XuDepartment of Breast Surgery, First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Yong-Xi SongDepartment of Surgical Oncology, First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Zhong-Ran NiDepartment of Surgical Oncology, First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Hao XuDepartment of Medical Oncology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.
Song-Cheng YinDepartment of Surgical Oncology, First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Xing-Yu LiuDepartment of Surgical Oncology, First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Zhi-Feng MiaoDepartment of Surgical Oncology, First Hospital of China Medical University, Shenyang, Liaoning Province, China.
First Hospital of China Medical University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol consumption is inconsistently associated with the risk of gastric cancer morbidity and mortality. The aim of this study was to systematically evaluate the association between alcohol consumption on gastric cancer risk. The PubMed, Embase, and Cochrane Library databases were searched from inception through April 2017. Prospective cohort studies evaluating the association between alcohol consumption and risk of gastric cancer which report its effect estimates with 95% confidence intervals (CIs) were included. The results summary was performed using the random-effect model. Twenty-two cohort studies involving 22,545 cases of gastric cancer and 5,820,431 participants were identified and included in our data analysis. Overall, drinking had little or no effect on gastric cancer as compared with non-drinkers. Furthermore, light and moderate alcohol consumption had no significant effect on gastric cancer risk when compared with non-drinkers. However, heavy alcohol consumption was associated with a greater risk of gastric cancer when compared with non-drinkers. The findings of the subgroup analyses indicated that light alcohol consumption was associated with a lower risk of gastric cancer in women, while heavy alcohol consumption was associated with an increased risk of gastric cancer regardless of country, gender, whether the study reported gastric cancer incidence, or whether the study adjusted for body mass index, educational attainment, or physical activity. The findings of this study suggest that light alcohol consumption might play a protective effect on gastric cancer in women, while heavy alcohol consumption is associated with a significantly increased risk of gastric cancer in all subgroups.

Indexed as

alcohol consumptioncancer riskgastric cancerheavy alcohol consumptionmeta-analysis

Identifiers

PMID29137439
PMCPMC5663611
OpenAlexW2755506889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.