Evidence map›Paper›PMID 29137429›Full record

ArticleOncotarget2017

Survival rate variation with different histological subtypes of poor prognostic male anal squamous cell carcinoma: a population-based study.

Zihao Wan, Zhihao Huang, Vikash Vikash, Kelash Rai, Sindhu Vikash, Liaobin Chen, Jingfeng Li

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Zihao Wan *Department of Orthopaedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, China.
Zhihao Huang *Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, China.
Vikash Vikash *Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China.
Kelash RaiDepartment of Medicine, Ziauddin Hospital, Karachi, Sindh, Pakistan.
Sindhu VikashDepartment of Medicine, Chandka Medical College, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Sindh, Pakistan.
Liaobin ChenDepartment of Orthopaedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, China.
Jingfeng LiDepartment of Orthopaedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, China.
Zhongnan Hospital of Wuhan University · CNWuhan University · CNChandka Medical College · PKZiauddin Hospital · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveThe prognosis of male anal squamous cell carcinoma (MASCC) and female anal squamous cell carcinoma (FASCC) is variable. The influence of tumor subtype on the survival rate and gender is poorly known. Our study is the largest population-based study and aims to outline the difference in survival between MASCC and FASCC patients.

methodsA retrospective population-based study was performed to compare the disease-specific mortalities (DSMs) between genders related to the tumor subtypes. The Surveillance, Epidemiology, and End Results (SEER) program database was employed to obtain the data from January 1988 to December 2014.

resultsA total of 4,516, (3,249 males and 1,267 females), patients with anal squamous cell carcinomas (ASCC) were investigated. The 5-year DSMs were 24.18% and 18.08% for men and women, respectively. The univariate analysis of the male basaloid squamous cell carcinoma (BSCC) and cloacogenic carcinoma (CC) patients demonstrated higher DSMs (P <0.001). Moreover, in the multivariate analysis, BSCC and CC were associated with soaring DSMs in male patients (P < 0.05).

conclusionsIn the cohort of BSCC and CC patients, male patients demonstrated a considerable decrease in survival rate compared to females. A more precise classification of ASCC and individualized management for MASCC are warranted.

Indexed as

anus squamous cell carcinomamaleretrospective cohort studySEER databasetumor subtype

Identifiers

PMID29137429
PMCPMC5663601
OpenAlexW2755425696

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.