Evidence map›Paper›PMID 29137419›Full record

ArticleOncotarget2017

Caspase-3 expression in tumorigenesis and prognosis of buccal mucosa squamous cell carcinoma.

Jer-Shyung Huang, Cheng-Mei Yang, Jyh-Seng Wang, Huei-Han Liou, I-Chien Hsieh, Guan-Cheng Li, Sin-Jhih Huang, Chih-Wen Shu, Ting-Ying Fu, Yun-Chung Lin and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  13. Debris-stimulated tumor growth: a Pandora's box?Cancer metastasis reviews · 2021
    Review
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  15. Mutagenic Consequences of Sublethal Cell Death Signaling.International journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jer-Shyung Huang *Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Cheng-Mei Yang *Department of Stomatology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Jyh-Seng WangDepartment of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Huei-Han LiouDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
I-Chien HsiehDepartment of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Guan-Cheng LiDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Sin-Jhih HuangDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Chih-Wen ShuDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Ting-Ying FuDepartment of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Yun-Chung LinDepartment of Pathology, China Medical University Hospital, Taichung, Taiwan.
Luo-Ping GerDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Pei-Feng LiuDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Kaohsiung Veterans General Hospital · TWChina Medical University Hospital · TWMin-Hwei College of Health Care Management · TWNational Sun Yat-sen University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Buccal mucosa squamous cell carcinoma (BMSCC) is the most common oral cancer in Southeast Asia. Caspase-3, a key molecule in regulating apoptosis, promotes the malignancy of various cancers. However, its role in BMSCC is unknown. Herein, we evaluated the association of caspase-3 expression with tumorigenesis and prognosis in BMSCC patients. Immunohistochemical staining indicated that the expression levels of cleaved caspase-3 (

Indexed as

buccal mucosa squamous cell carcinomacaspase-3cleaved caspase-3prognosistumorigenesis

Identifiers

PMID29137419
PMCPMC5663591
OpenAlexW2746676566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.