Evidence map›Paper›PMID 29137368›Full record

ArticleOncotarget2017

The protective effects of carboxyhemoglobin during the resuscitation from hemorrhagic shock in rats.

Hongyu Liu, Songyan Yu, Yaojun Peng, Xin Chang, Xinguang Yu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hongyu LiuDepartment of Neurosurgery, Chinese PLA General Hospital, Beijing 100853, China.
Songyan YuDepartment of Endocrinology, Chinese PLA General Hospital, Beijing 100853, China.
Yaojun PengKey Laboratory of Cancer Center, Chinese PLA General Hospital, Beijing 100853, China.
Xin ChangDepartment of Clinical Laboratory, Weihai Municipal Hospital, Weihai 264200, Shandong, China.
Xinguang YuDepartment of Neurosurgery, Chinese PLA General Hospital, Beijing 100853, China.
Chinese PLA General Hospital · CNWeihai Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study was aimed to explore the effects of carboxyhemoglobin on reperfusion injury in hemorrhagic shock, as well as its action time and related mechanisms.

resultsCO-RBC group showed milder oxidative injury than O2-RBC group. CO reperfusion did not show advantages in functions of kidney and lung during resuscitation. The level of MATERIALS AND

methodsThe hemorrhagic shock model rats were randomly divided into: the hemorrhagic shock group (

conclusionsCarboxyhemoglobin not only relieves the oxidative injury and inhibites apoptosis and autophagy, but also aggravates inflammatory reactions during reperfusion. The action time of carboxyhemoglobin may be an influencing factor for reperfusion outcomes.

Indexed as

CO-red blood cells resuscitationinflammatory reactionoxidative injuryresuscitation from hemorrhagic shock

Identifiers

PMID29137368
PMCPMC5663540
OpenAlexW2729920211

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.