Evidence map›Paper›PMID 29137250›Full record

ArticleOncotarget2017

Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated

Zuzanna Tracz-Gaszewska, Marta Klimczak, Przemyslaw Biecek, Marcin Herok, Marcin Kosinski, Maciej B Olszewski, Patrycja Czerwińska, Milena Wiech, Maciej Wiznerowicz, Alicja Zylicz and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. TP53 mutations and MDM2 polymorphisms in breast and ovarian cancers: amelioration by drugs and natural compounds.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
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  12. CaCancer science · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Zuzanna Tracz-GaszewskaInternational Institute of Molecular and Cell Biology, Warsaw, Poland.
Marta KlimczakInternational Institute of Molecular and Cell Biology, Warsaw, Poland.
Przemyslaw BiecekFaculty of Mathematics, Informatics, and Mechanics, University of Warsaw, Warsaw, Poland.
Marcin HerokInternational Institute of Molecular and Cell Biology, Warsaw, Poland.
Marcin KosinskiFaculty of Mathematics and Information Science, Warsaw University of Technology, Warsaw, Poland.
Maciej B OlszewskiInternational Institute of Molecular and Cell Biology, Warsaw, Poland.
Patrycja CzerwińskaInternational Institute of Molecular and Cell Biology, Warsaw, Poland.
Milena WiechInternational Institute of Molecular and Cell Biology, Warsaw, Poland.
Maciej WiznerowiczLaboratory of Gene Therapy, Department of Cancer Immunology, The Greater Poland Cancer Center, Poznan, Poland.
Alicja ZyliczInternational Institute of Molecular and Cell Biology, Warsaw, Poland.
Maciej ZyliczInternational Institute of Molecular and Cell Biology, Warsaw, Poland.
Bartosz WawrzynowInstitute of Biochemistry and Biophysics, PAS, Warsaw, Poland.
International Institute of Molecular and Cell Biology · PLGreater Poland Cancer Center · PLInstitute of Biochemistry and Biophysics, Polish Academy of Sciences · PLWarsaw University of Technology · PLPostgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Utilizing the TCGA PANCAN12 dataset we discovered that cancer patients with mutations in

Indexed as

apoptosisheat shock protein (HSP)mouse double minute 2 homolog (MDM2)mutant p53 gain-of-functionp73 tumor suppressor

Identifiers

PMID29137250
PMCPMC5669876
OpenAlexW2726844625

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.