Evidence map›Paper›PMID 29137169›Full record

ReviewNutrients2017

Pancreatic Exocrine Insufficiency after Bariatric Surgery.

Miroslav Vujasinovic, Roberto Valente, Anders Thorell, Wiktor Rutkowski, Stephan L Haas, Urban Arnelo, Lena Martin, J-Matthias Löhr

Abstract readReview
In one paragraph

Review in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Pancreatic exocrine insufficiency.EClinicalMedicine · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miroslav VujasinovicCenter for Digestive Diseases, Karolinska University Hospital, SE-141 86 Stockholm, Sweden. miroslav.vujasinovic@sll.se.
Roberto ValenteCenter for Digestive Diseases, Karolinska University Hospital, SE-141 86 Stockholm, Sweden. roberto.valente@karolinska.se.
Anders ThorellDepartment of Clinical Science, Danderyd Hospital, Karolinska Institutet and Department of Surgery, Ersta Hospital, SE-116 91 Stockholm, Sweden. anders.thorell@erstadiakoni.se.
Wiktor RutkowskiCenter for Digestive Diseases, Karolinska University Hospital, SE-141 86 Stockholm, Sweden. wikru@hotmail.com.
Stephan L HaasCenter for Digestive Diseases, Karolinska University Hospital, SE-141 86 Stockholm, Sweden. stephan.haas@karolinska.se.
Urban ArneloCenter for Digestive Diseases, Karolinska University Hospital, SE-141 86 Stockholm, Sweden. urban.arnelo@sll.se.
Lena MartinCenter for Digestive Diseases, Karolinska University Hospital, SE-141 86 Stockholm, Sweden. lena.martin@sll.se.
J-Matthias LöhrCenter for Digestive Diseases, Karolinska University Hospital, SE-141 86 Stockholm, Sweden. matthias.lohr@ki.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Morbid obesity is a lifelong disease, and all patients require complementary follow-up including nutritional surveillance by a multidisciplinary team after bariatric procedures. Pancreatic exocrine insufficiency (PEI) refers to an insufficient secretion of pancreatic enzymes and/or sodium bicarbonate. PEI is a known multifactorial complication after upper gastrointestinal surgery, and might constitute an important clinical problem due to the large number of bariatric surgical procedures in the world. Symptoms of PEI often overlap with sequelae of gastric bypass, making the diagnosis difficult. Steatorrhea, weight loss, maldigestion and malabsorption are pathognomonic for both clinical conditions. Altered anatomy after bypass surgery can make the diagnostic process even more difficult. Fecal elastase-1 (FE1) is a useful diagnostic test. PEI should be considered in all patients after bariatric surgery with prolonged gastrointestinal complaints that are suggestive of maldigestion and/or malabsorption. Appropriate pancreatic enzyme replacement therapy should be part of the treatment algorithm in patients with confirmed PEI or symptoms suggestive of this complication.

Indexed as

Bariatric SurgeryBiomarkersEnzyme Replacement TherapyExocrine Pancreatic InsufficiencyFecesHumansObesity, MorbidPancreatic ElastasePredictive Value of TestsRisk FactorsTreatment OutcomeBiomarkersPancreatic Elastasebariatric surgeryexocrineinsufficiencyobesitypancreas

Identifiers

PMID29137169
PMCPMC5707713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.