Evidence map›Paper›PMID 29137134›Full record

ReviewMetabolites2017

An Overview of the Bacterial Carbonic Anhydrases.

Claudiu T Supuran, Clemente Capasso

Abstract readReview
In one paragraph

Review in Metabolites, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed.

  1. Review
  2. Article
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  4. Review
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  14. Challenges and Prospects for Eradication ofPathogens (Basel, Switzerland) · 2025
    Review
  15. Article
  16. Candidate transmission survival genome ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Mineral Carbonation for Carbon Sequestration: A Case for MCP and MICP.International journal of molecular sciences · 2025
    Review
  18. Article
  19. Article
  20. Article

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Claudiu T SupuranDipartimento Neurofarba, Sezione di Scienze Farmaceutiche, Laboratorio di Chimica Bioinorganica, Università degli Studi di Firenze, Polo Scientifico, Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy. claudiu.supuran@unifi.it.ORCID 0000-0003-4262-0323
Clemente CapassoIstituto di Bioscienze e Biorisorse (IBBR), Consiglio Nazionale delle Ricerche (CNR), via Pietro Castellino 111, 80131 Napoli, Italy. clemente.capasso@ibbr.cnr.it.ORCID 0000-0003-3314-2411

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria encode carbonic anhydrases (CAs, EC 4.2.1.1) belonging to three different genetic families, the α-, β-, and γ-classes. By equilibrating CO₂ and bicarbonate, these metalloenzymes interfere with pH regulation and other crucial physiological processes of these organisms. The detailed investigations of many such enzymes from pathogenic and non-pathogenic bacteria afford the opportunity to design both novel therapeutic agents, as well as biomimetic processes, for example, for CO₂ capture. Investigation of bacterial CA inhibitors and activators may be relevant for finding antibiotics with a new mechanism of action.

Indexed as

antibioticbacterial carbonic anhydrasesCO2 captureengineered bacteriainhibitors

Identifiers

PMID29137134
PMCPMC5746736

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.