Evidence map›Paper›PMID 29136537›Full record

ReviewCurrent opinion in microbiology2017

New advances in understanding the host immune response to Pneumocystis.

J Claire Hoving, Jay K Kolls

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Fungal Infections in Disorders of Inborn Errors of Immunity.Clinical reviews in allergy & immunology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Immune responses of different hosts toEuropean respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  7. An Observational Analysis of a Large Cohort ofOpen forum infectious diseases · 2025
    Article
  8. Article
  9. Article
  10. CMV Infection and Lymphopenia: Warning Markers ofTransplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  11. Review
  12. Targeted NGS-Based Analysis ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

J Claire HovingInstitute of Infectious Disease and Molecular Medicine (IDM), Department of Pathology, Faculty of Health Sciences, University of Cape Town, South Africa. Electronic address: Jennifer.hoving@uct.ac.za.
Jay K KollsCenter for Translational Research in Infection and Inflammation, Tulane School of Medicine, New Orleans, USA. Electronic address: jkolls1@tulane.edu.
Tulane University · USUniversity of Cape Town · ZA

Funding

T-Cells and P. Carinii PneumoniaR01HL062052 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOLLS, JAY K · 1998 to 2017
$5.1M
Improved Therapeutics and Diagnostics for PneumocystisPneumoniaR01AI120033 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JAY K KOLLS · 2016 to 2026
$4.8M
NHLBI NIH HHS R01 HL062052NIAID NIH HHS R01 AI120033
6 · The paper itself

Abstract

Pneumocystis jirovecii causes clinical pneumonia in immunocompromised hosts. Despite this, the inability to cultivate this organism in vitro has likely hindered the field in ascertaining the true impact of Pneumocystis in human infection. However the recent release of the genome as well as in advances in understanding host genetics, and other risk factors for infection and robust experimental models of disease have shed new light on the impact of this fungal pathogen as to better define populations at risk. This review will highlight these recent advances as well as highlight future needed areas of research.

Indexed as

AnimalsHumansPneumocystis cariniiPneumonia, Pneumocystis

Identifiers

PMID29136537
PMCPMC5733705
OpenAlexW2767587000

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.