Evidence map›Paper›PMID 29136219›Full record

ArticleNucleic acids research2018

MobiDB 3.0: more annotations for intrinsic disorder, conformational diversity and interactions in proteins.

Damiano Piovesan, Francesco Tabaro, Lisanna Paladin, Marco Necci, Ivan Micetic, Carlo Camilloni, Norman Davey, Zsuzsanna Dosztányi, Bálint Mészáros, Alexander M Monzon and 7 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed.

  1. Article
  2. Review
  3. Regulation of vacuole fusion in stomata by dephosphorylation of the HOPS subunit VPS39.The Plant journal : for cell and molecular biology · 2025
    Article
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  5. Biomolecular condensates and disease pathogenesis.Science China. Life sciences · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Computational prediction of disordered binding regions.Computational and structural biotechnology journal · 2023
    Review
  17. Modeling of Protein Complexes.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  18. PeerJ · 2023
    Article
  19. Review
  20. Lighting up Nobel Prize-winning studies with protein intrinsic disorder.Cellular and molecular life sciences : CMLS · 2022
    Review

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Damiano PiovesanDepartment of Biomedical Sciences, University of Padua, via U. Bassi 58/b, 35131 Padua, Italy.
Francesco TabaroDepartment of Biomedical Sciences, University of Padua, via U. Bassi 58/b, 35131 Padua, Italy.
Lisanna PaladinDepartment of Biomedical Sciences, University of Padua, via U. Bassi 58/b, 35131 Padua, Italy.
Marco NecciDepartment of Biomedical Sciences, University of Padua, via U. Bassi 58/b, 35131 Padua, Italy.
Ivan MiceticDepartment of Biomedical Sciences, University of Padua, via U. Bassi 58/b, 35131 Padua, Italy.
Carlo CamilloniDepartment of Biosciences, University of Milan, 20133 Milano, Italy.
Norman DaveyConway Institute of Biomolecular & Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.
Zsuzsanna DosztányiMTA-ELTE Lendület Bioinformatics Research Group, Department of Biochemistry, Eötvös Loránd University, 1/c Pázmány Péter sétány, H-1117, Budapest, Hungary.
Bálint MészárosMTA-ELTE Lendület Bioinformatics Research Group, Department of Biochemistry, Eötvös Loránd University, 1/c Pázmány Péter sétány, H-1117, Budapest, Hungary.
Alexander M MonzonStructural Bioinformatics Group, Department of Science and Technology, National University of Quilmes, CONICET, Roque Saenz Pena 182, Bernal B1876BXD, Argentina.
Gustavo ParisiStructural Bioinformatics Group, Department of Science and Technology, National University of Quilmes, CONICET, Roque Saenz Pena 182, Bernal B1876BXD, Argentina.
Eva SchadInstitute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, PO Box 7, H-1518 Budapest, Hungary.
Pietro SormanniDepartment of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
Peter TompaInstitute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, PO Box 7, H-1518 Budapest, Hungary.
Michele VendruscoloDepartment of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
Wim F VrankenStructural Biology Brussels, Vrije Universiteit Brussel (VUB), Brussels 1050, Belgium.
Silvio C E TosattoDepartment of Biomedical Sciences, University of Padua, via U. Bassi 58/b, 35131 Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The MobiDB (URL: mobidb.bio.unipd.it) database of protein disorder and mobility annotations has been significantly updated and upgraded since its last major renewal in 2014. Several curated datasets for intrinsic disorder and folding upon binding have been integrated from specialized databases. The indirect evidence has also been expanded to better capture information available in the PDB, such as high temperature residues in X-ray structures and overall conformational diversity. Novel nuclear magnetic resonance chemical shift data provides an additional experimental information layer on conformational dynamics. Predictions have been expanded to provide new types of annotation on backbone rigidity, secondary structure preference and disordered binding regions. MobiDB 3.0 contains information for the complete UniProt protein set and synchronization has been improved by covering all UniParc sequences. An advanced search function allows the creation of a wide array of custom-made datasets for download and further analysis. A large amount of information and cross-links to more specialized databases are intended to make MobiDB the central resource for the scientific community working on protein intrinsic disorder and mobility.

Indexed as

Databases, ProteinMolecular Sequence AnnotationSoftwareAmino Acid SequenceBinding SitesDatasets as TopicGene OntologyHumansInternetIntrinsically Disordered ProteinsModels, MolecularProtein BindingProtein FoldingProtein Interaction Domains and MotifsSequence AlignmentIntrinsically Disordered Proteins

Identifiers

PMID29136219
PMCPMC5753340

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.