ArticleCerebral cortex (New York, N.Y. : 1991)2019
The Laminar Organization of Piriform Cortex Follows a Selective Developmental and Migratory Program Established by Cell Lineage.
Article in Cerebral cortex (New York, N.Y. : 1991), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 66 citations in OpenAlex.
- Comparative Cilia Analysis in the Cerebral Cortices of Turtles, Mice, and Macaques.bioRxiv : the preprint server for biology · 2025Article
- Reelin Controls the Directional Orientation, Apical Localization and Length of Primary Cilia in Principal Neurons in the Cerebral Cortex.bioRxiv : the preprint server for biology · 2025Article
- Olfactory bulb interneurons - The developmental timeline and targeting defined by embryonic neurogenesis.Molecular and cellular neurosciences · 2025Article
- Timing Matters: Lessons From Perinatal Neurogenesis in the Olfactory Bulb.The Journal of comparative neurology · 2025Article
- Olfactory Development and Dysfunction: Involvement of Microglia.Physiology (Bethesda, Md.) · 2025Review
- Laminar organization of the anterior olfactory nucleus-the interplay between neurogenesis timing and neuroblast migration.Frontiers in neuroscience · 2025Article
- Common principles for odour coding across vertebrates and invertebrates.Nature reviews. Neuroscience · 2024Review
- Article
- Effects of prenatal alcohol exposure on the olfactory system development.Frontiers in neural circuits · 2024Review
- Calcium Channels and Calcium-Binding Proteins.International journal of molecular sciences · 2023Article
- α-Synuclein Pathology and Reduced Neurogenesis in the Olfactory System Affect Olfaction in a Mouse Model of Parkinson's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Lineage Relationships Between Subpallial Progenitors and Glial Cells in the Piriform Cortex.Frontiers in neuroscience · 2022Article
- Age-Dependent Contributions of NMDA Receptors and L-Type Calcium Channels to Long-Term Depression in the Piriform Cortex.International journal of molecular sciences · 2021Article
- Specific contribution of neurons from the Dbx1 lineage to the piriform cortex.Scientific reports · 2021Article
- An Evolutionary Microcircuit Approach to the Neural Basis of High Dimensional Sensory Processing in Olfaction.Frontiers in cellular neuroscience · 2021Article
- Pyramidal Cells in Olfactory Cortex.Chemical senses · 2021Article
- Sequential pattern of sublayer formation in the paleocortex and neocortex.Medical molecular morphology · 2020Article
- Embryonic and postnatal development of mouse olfactory tubercle.Molecular and cellular neurosciences · 2019Article
- Combining near-infrared fluorescence with Brainbow to visualize expression of specific genes within a multicolor context.Molecular biology of the cell · 2019Article
- Development of piriform cortex interhemispheric connections via the anterior commissure: progressive and regressive strategies.Brain structure & function · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Piriform cortex (PC) is a 3-layer paleocortex receiving primary afferent input from the olfactory bulb. The past decade has seen significant progress in understanding the synaptic, cellular and functional organization of PC, but PC embryogenesis continues to be enigmatic. Here, using birthdating strategies and clonal analyses, we probed the early development and laminar specificity of neurogenesis/gliogenesis as it relates to the organization of the PC. Our data demonstrate a temporal sequence of laminar-specific neurogenesis following the canonical "inside-out" pattern, with the notable exception of PC Layer II which exhibited an inverse "outside-in" temporal neurogenic pattern. Of interest, we found no evidence of a neurogenic gradient along the anterior to posterior axis, although the timing of neuronal migration and laminar development was delayed rostrally by approximately 24 h. To begin probing if lineage affected cell fate in the PC, we labeled PC neuroblasts using a multicolor technique and analyzed their laminar organization. Our results suggested that PC progenitors were phenotypically committed to reach specific layers early in the development. Collectively, these studies shed new light on the determinants of the laminar specificity of neuronal/glial organization in PC and the likely role of subpopulations of committed progenitors in regulating PC embryogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.